EP3 antagonist 4

Modify Date: 2024-01-02 17:49:39

EP3 antagonist 4 Structure
EP3 antagonist 4 structure
 Common Name EP3 antagonist 4
CAS Number 2408297-80-1 Molecular Weight 577.91
Density N/A Boiling Point N/A
Molecular Formula C22H20Cl3FN4O3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EP3 antagonist 4


EP3 antagonist 4 (Compound 28) is an EP3 antagonist, with a Ki value of 2 nM for hEP. EP3 antagonist 4 shows low in vivo clearance, high oral AUC, and good bioavailability in the rat full PK studies. EP3 antagonist 4 can be used for research of beta cell dysfunction in diabetes[1].

 Names

Name EP3 antagonist 4

 EP3 antagonist 4 Biological Activity

Description EP3 antagonist 4 (Compound 28) is an EP3 antagonist, with a Ki value of 2 nM for hEP. EP3 antagonist 4 shows low in vivo clearance, high oral AUC, and good bioavailability in the rat full PK studies. EP3 antagonist 4 can be used for research of beta cell dysfunction in diabetes[1].
Related Catalog
References

[1]. Zhu B, et al. Discovery and Optimization of 7-Alkylidenyltetrahydroindazole-Based Acylsulfonamide EP3 Antagonists. ACS Med Chem Lett. 2021 Dec 7;13(1):111-117.  

 Chemical & Physical Properties

Molecular Formula C22H20Cl3FN4O3S2
Molecular Weight 577.91
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Chemsrc provides EP3 antagonist 4(CAS#:2408297-80-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of EP3 antagonist 4 are included as well.>> amp version: EP3 antagonist 4

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