EP3 antagonist 4

Modify Date: 2024-01-02 17:49:39

EP3 antagonist 4 structure	Common Name	EP3 antagonist 4
	CAS Number	2408297-80-1	Molecular Weight	577.91
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₀Cl₃FN₄O₃S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of EP3 antagonist 4

EP3 antagonist 4 (Compound 28) is an EP3 antagonist, with a Ki value of 2 nM for hEP. EP3 antagonist 4 shows low in vivo clearance, high oral AUC, and good bioavailability in the rat full PK studies. EP3 antagonist 4 can be used for research of beta cell dysfunction in diabetes[1].

Name	EP3 antagonist 4

Description	EP3 antagonist 4 (Compound 28) is an EP3 antagonist, with a Ki value of 2 nM for hEP. EP3 antagonist 4 shows low in vivo clearance, high oral AUC, and good bioavailability in the rat full PK studies. EP3 antagonist 4 can be used for research of beta cell dysfunction in diabetes[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Metabolic Disease
References	[1]. Zhu B, et al. Discovery and Optimization of 7-Alkylidenyltetrahydroindazole-Based Acylsulfonamide EP3 Antagonists. ACS Med Chem Lett. 2021 Dec 7;13(1):111-117.

Molecular Formula	C₂₂H₂₀Cl₃FN₄O₃S₂
Molecular Weight	577.91

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EP3 antagonist 4

Use of EP3 antagonist 4

Names

EP3 antagonist 4 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.