Fmoc-L-Lys(N3-Aca-DIM)-OH

Modify Date: 2025-11-25 10:48:42

Fmoc-L-Lys(N3-Aca-DIM)-OH Structure
Fmoc-L-Lys(N3-Aca-DIM)-OH structure
Common Name Fmoc-L-Lys(N3-Aca-DIM)-OH
CAS Number 2408993-39-3 Molecular Weight 629.75
Density N/A Boiling Point N/A
Molecular Formula C35H43N5O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Fmoc-L-Lys(N3-Aca-DIM)-OH


Fmoc-L-Lys(N3-Aca-DIM)-OH is a click chemistry reagent containing an azide group. Used as a SPPS building-block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution[1].

 Names

Name Fmoc-L-Lys(N3-Aca-DIM)-OH

 Fmoc-L-Lys(N3-Aca-DIM)-OH Biological Activity

Description Fmoc-L-Lys(N3-Aca-DIM)-OH is a click chemistry reagent containing an azide group. Used as a SPPS building-block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution[1].
Related Catalog
References

[1]. Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789.  

 Chemical & Physical Properties

Molecular Formula C35H43N5O6
Molecular Weight 629.75
InChIKey BFEOBKQXWBSIEV-LJAQVGFWSA-N
SMILES CC1(C)CC(=O)C(C(CCCCCN=[N+]=[N-])=NCCCCC(NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)=C(O)C1
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