THK-5470

Modify Date: 2025-09-03 11:12:22

THK-5470 Structure
THK-5470 structure
Common Name THK-5470
CAS Number 2410554-04-8 Molecular Weight 312.34
Density N/A Boiling Point N/A
Molecular Formula C18H17FN2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of THK-5470


THK-5470, a monoamine oxidase-B (MAO-B) imaging probe, could be used for neurological diseases study. THK-5470 shows remarkably high binding affinity against MAO-B with an IC50 value of 4.2 nM, low binding affinity against tau with an IC50 value of 4462 nM. THK-5470 has high selective binding property and high affinity (from patent EP2019-846498).

 Names

Name THK-5470

 THK-5470 Biological Activity

Description THK-5470, a monoamine oxidase-B (MAO-B) imaging probe, could be used for neurological diseases study. THK-5470 shows remarkably high binding affinity against MAO-B with an IC50 value of 4.2 nM, low binding affinity against tau with an IC50 value of 4462 nM. THK-5470 has high selective binding property and high affinity (from patent EP2019-846498).
Related Catalog
Target

THK-5470 shows remarkably high binding affinity against MAO-B with an IC50 value of 4.2 nM, low binding affinity against tau with an IC50 value of 4462 nM.

 Chemical & Physical Properties

Molecular Formula C18H17FN2O2
Molecular Weight 312.34
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