THK-5117
Modify Date: 2025-08-27 18:53:21
THK-5117 structure
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Common Name | THK-5117 | ||
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| CAS Number | 1374107-54-6 | Molecular Weight | 326.36500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H19FN2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of THK-5117THK-5117, an arylquinoline derivative, displays high binding affinity to tau fibrils with a Ki of 10.5 nM. THK-5117 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD) brain homogenates. 18F-THK-5117 has the potential to act as a tau imaging PET probe[1]. |
| Name | thk-5117 |
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| Synonym | More Synonyms |
| Description | THK-5117, an arylquinoline derivative, displays high binding affinity to tau fibrils with a Ki of 10.5 nM. THK-5117 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD) brain homogenates. 18F-THK-5117 has the potential to act as a tau imaging PET probe[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C19H19FN2O2 |
|---|---|
| Molecular Weight | 326.36500 |
| Exact Mass | 326.14300 |
| PSA | 54.38000 |
| LogP | 3.72570 |
| 6-[(3-fluoro-2-hydroxy)propoxy]-2-(4-methylaminophenyl)quinoline |