ARUK3001185

Modify Date: 2024-01-10 19:05:26

ARUK3001185 Structure
ARUK3001185 structure
 Common Name ARUK3001185
CAS Number 2411969-39-4 Molecular Weight 282.05
Density N/A Boiling Point N/A
Molecular Formula C9H4Cl2F3N3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ARUK3001185


ARUK3001185 (Compound 8l) is a potent, selective, orally active and brain-penetrant inhibitor of Notum activity with an IC50 of 6.7 nM[1].

 Names

Name ARUK3001185

 ARUK3001185 Biological Activity

Description ARUK3001185 (Compound 8l) is a potent, selective, orally active and brain-penetrant inhibitor of Notum activity with an IC50 of 6.7 nM[1].
Related Catalog
Target

IC50: 6.7 nM (Notum)[1]

References

[1]. Willis NJ, et al. Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit. J Med Chem. 2022 May 26;65(10):7212-7230.

 Chemical & Physical Properties

Molecular Formula C9H4Cl2F3N3
Molecular Weight 282.05
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Chemsrc provides ARUK3001185(CAS#:2411969-39-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of ARUK3001185 are included as well.>> amp version: ARUK3001185

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