HKB99
Modify Date: 2024-04-02 18:27:38
HKB99 structure
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Common Name | HKB99 | ||
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| CAS Number | 2414908-90-8 | Molecular Weight | 450.46 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H18N2O6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HKB99HKB99 is an allosteric inhibitor of phosphoglycerate mutase 1 (PGAM1). HKB99 inhibits the formation of invasive pseudopodia and increases the level of PAI-2 in vitro. HKB99 increases the oxidative stress, activates JNK/c-Jun and suppresses AKT and ERK. HKB99 can be used for the research of non-small-cell lung cancer (NSCLC)[1][2]. |
| Name | HKB99 |
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| Description | HKB99 is an allosteric inhibitor of phosphoglycerate mutase 1 (PGAM1). HKB99 inhibits the formation of invasive pseudopodia and increases the level of PAI-2 in vitro. HKB99 increases the oxidative stress, activates JNK/c-Jun and suppresses AKT and ERK. HKB99 can be used for the research of non-small-cell lung cancer (NSCLC)[1][2]. |
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| Molecular Formula | C23H18N2O6S |
|---|---|
| Molecular Weight | 450.46 |
| InChIKey | ZSFURBMYHHMIKE-UHFFFAOYSA-N |
| SMILES | O=C1c2ccccc2C(=O)c2c1cc(NS(=O)(=O)c1ccc(N3CCC3)cc1)c(O)c2O |