KB-0742 dihydrochloride

Modify Date: 2024-01-14 10:35:58

KB-0742 dihydrochloride Structure
KB-0742 dihydrochloride structure
Common Name KB-0742 dihydrochloride
CAS Number 2416874-75-2 Molecular Weight 360.33
Density N/A Boiling Point N/A
Molecular Formula C16H27Cl2N5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of KB-0742 dihydrochloride


KB-0742 dihydrochloride is a potent, selective and orally active CDK9 inhibitor with an IC50 of 6 nM for CDK9/cyclin T1. KB-0742 dihydrochloride is selective for CDK9/cyclin T1 with >50-fold selectivity over other CDK kinases. KB-0742 dihydrochloride has potent anti-tumor activity.

 Names

Name KB-0742 dihydrochloride

 KB-0742 dihydrochloride Biological Activity

Description KB-0742 dihydrochloride is a potent, selective and orally active CDK9 inhibitor with an IC50 of 6 nM for CDK9/cyclin T1. KB-0742 dihydrochloride is selective for CDK9/cyclin T1 with >50-fold selectivity over other CDK kinases. KB-0742 dihydrochloride has potent anti-tumor activity.

 Chemical & Physical Properties

Molecular Formula C16H27Cl2N5
Molecular Weight 360.33
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