PFI-5

Modify Date: 2024-04-08 22:25:51

PFI-5 Structure
PFI-5 structure
Common Name PFI-5
CAS Number 2423057-75-2 Molecular Weight 501.679
Density N/A Boiling Point N/A
Molecular Formula C29H39N7O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PFI-5


PFI-5 a highly biochemically potent, selective, and cell-active SMYD2 chemical probe with IC50 of 8 nM.PFI-5 inhibits p53 methylation in MCF7 cells with EC50 of 1.3 uM, with no toxicity.

 Names

Name PFI-5

 PFI-5 Biological Activity

Description PFI-5 a highly biochemically potent, selective, and cell-active SMYD2 chemical probe with IC50 of 8 nM.PFI-5 inhibits p53 methylation in MCF7 cells with EC50 of 1.3 uM, with no toxicity.
References 1. Taylor AP, et al. J Med Chem. 2019 Sep 12;62(17):7669-7683.

 Chemical & Physical Properties

Molecular Formula C29H39N7O
Molecular Weight 501.679