NSC 131114

Modify Date: 2024-01-05 17:47:00

NSC 131114 structure	Common Name	NSC 131114
	CAS Number	24425-56-7	Molecular Weight	391.48300
	Density	1.254g/cm3	Boiling Point	748.5ºC at 760 mmHg
	Molecular Formula	C₁₆H₂₉N₃O₆S	Melting Point	200-202ºC(lit.)
	MSDS	Chinese USA	Flash Point	406.5ºC

Use of NSC 131114

S-Hexylglutathione is an S-substituted glutathione in which the hydrogen of the thiol has been replaced by a hexyl group. S-Hexylglutathione is also an competitive inhibitor against glutathione-S-transferase. S-Hexylglutathione can be used as an affinity chromatographic ligand for glutathione-S-transferase and glutathione peroxidase[1][2].

Name	S-hexylglutathione
Synonym	More Synonyms

Description	S-Hexylglutathione is an S-substituted glutathione in which the hydrogen of the thiol has been replaced by a hexyl group. S-Hexylglutathione is also an competitive inhibitor against glutathione-S-transferase. S-Hexylglutathione can be used as an affinity chromatographic ligand for glutathione-S-transferase and glutathione peroxidase[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	S-Hexylglutathione is bound by human glutathione transferase P1-1 with Kd values of 3.7 μM (Y49F mutant) and 1.27 μM (wild-type), respectively[1].

Density	1.254g/cm3
Boiling Point	748.5ºC at 760 mmHg
Melting Point	200-202ºC(lit.)
Molecular Formula	C₁₆H₂₉N₃O₆S
Molecular Weight	391.48300
Flash Point	406.5ºC
Exact Mass	391.17800
PSA	184.12000
LogP	1.65970
Vapour Pressure	1.61E-24mmHg at 25°C
Index of Refraction	1.54

NSC 131114 MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2930909090

Glutathione

CAS#:70-18-8

1-Iodohexane

CAS#:638-45-9

NSC 131114

CAS#:24425-56-7

Literature: Miyaura; Isono Chemical and pharmaceutical bulletin, 1986 , vol. 34, # 1 p. 194 - 205

Precursor 2
CAS#:70-18-8 Glutathione CAS#:638-45-9 1-Iodohexane
DownStream 0

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Quantitation of protein S-glutathionylation by liquid chromatography-tandem mass spectrometry: correction for contaminating glutathione and glutathione disulfide.

Anal. Biochem. 469 , 54-64, (2014)

Protein S-glutathionylation is a posttranslational modification that links oxidative stimuli to reversible changes in cellular function. Protein-glutathione mixed disulfide (PSSG) is commonly quantifi...

Effects of ONO-6950, a novel dual cysteinyl leukotriene 1 and 2 receptors antagonist, in a guinea pig model of asthma.

Eur. J. Pharmacol. 765 , 242-8, (2015)

We assessed in this study the anti-asthmatic effects of ONO-6950, a novel cysteinyl leukotriene 1 (CysLT1) and 2 (CysLT2) receptors dual antagonist, in normal and S-hexyl glutathione (S-hexyl GSH)-tre...

Glutathionylation and Reduction of Methacrolein in Tomato Plants Account for Its Absorption from the Vapor Phase.

Plant Physiol. 169 , 1744-54, (2015)

A large portion of the volatile organic compounds emitted by plants are oxygenated to yield reactive carbonyl species, which have a big impact on atmospheric chemistry. Deposition to vegetation driven...

S-Hexylglutathione

MFCD00056735