NSC 131114

Modify Date: 2024-01-05 17:47:00

NSC 131114 Structure
NSC 131114 structure
Common Name NSC 131114
CAS Number 24425-56-7 Molecular Weight 391.48300
Density 1.254g/cm3 Boiling Point 748.5ºC at 760 mmHg
Molecular Formula C16H29N3O6S Melting Point 200-202ºC(lit.)
MSDS Chinese USA Flash Point 406.5ºC

 Use of NSC 131114


S-Hexylglutathione is an S-substituted glutathione in which the hydrogen of the thiol has been replaced by a hexyl group. S-Hexylglutathione is also an competitive inhibitor against glutathione-S-transferase. S-Hexylglutathione can be used as an affinity chromatographic ligand for glutathione-S-transferase and glutathione peroxidase[1][2].

 Names

Name S-hexylglutathione
Synonym More Synonyms

 NSC 131114 Biological Activity

Description S-Hexylglutathione is an S-substituted glutathione in which the hydrogen of the thiol has been replaced by a hexyl group. S-Hexylglutathione is also an competitive inhibitor against glutathione-S-transferase. S-Hexylglutathione can be used as an affinity chromatographic ligand for glutathione-S-transferase and glutathione peroxidase[1][2].
Related Catalog
In Vitro S-Hexylglutathione is bound by human glutathione transferase P1-1 with Kd values of 3.7 μM (Y49F mutant) and 1.27 μM (wild-type), respectively[1].

 Chemical & Physical Properties

Density 1.254g/cm3
Boiling Point 748.5ºC at 760 mmHg
Melting Point 200-202ºC(lit.)
Molecular Formula C16H29N3O6S
Molecular Weight 391.48300
Flash Point 406.5ºC
Exact Mass 391.17800
PSA 184.12000
LogP 1.65970
Vapour Pressure 1.61E-24mmHg at 25°C
Index of Refraction 1.54

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2930909090

 Synthetic Route

~%

NSC 131114 Structure

NSC 131114

CAS#:24425-56-7

Literature: Miyaura; Isono Chemical and pharmaceutical bulletin, 1986 , vol. 34, # 1 p. 194 - 205

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles37

More Articles
Quantitation of protein S-glutathionylation by liquid chromatography-tandem mass spectrometry: correction for contaminating glutathione and glutathione disulfide.

Anal. Biochem. 469 , 54-64, (2014)

Protein S-glutathionylation is a posttranslational modification that links oxidative stimuli to reversible changes in cellular function. Protein-glutathione mixed disulfide (PSSG) is commonly quantifi...

Effects of ONO-6950, a novel dual cysteinyl leukotriene 1 and 2 receptors antagonist, in a guinea pig model of asthma.

Eur. J. Pharmacol. 765 , 242-8, (2015)

We assessed in this study the anti-asthmatic effects of ONO-6950, a novel cysteinyl leukotriene 1 (CysLT1) and 2 (CysLT2) receptors dual antagonist, in normal and S-hexyl glutathione (S-hexyl GSH)-tre...

Glutathionylation and Reduction of Methacrolein in Tomato Plants Account for Its Absorption from the Vapor Phase.

Plant Physiol. 169 , 1744-54, (2015)

A large portion of the volatile organic compounds emitted by plants are oxygenated to yield reactive carbonyl species, which have a big impact on atmospheric chemistry. Deposition to vegetation driven...

 Synonyms

S-Hexylglutathione
MFCD00056735
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