Pomalidomide-C7-NH2 hydrochloride

Modify Date: 2025-09-27 11:04:31

Pomalidomide-C7-NH2 hydrochloride structure	Common Name	Pomalidomide-C7-NH2 hydrochloride
	CAS Number	2446474-05-9	Molecular Weight	422.91
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₇ClN₄O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Pomalidomide-C7-NH2 hydrochloride

Pomalidomide-C7-NH2 (Pomalidomide 4'-alkylC7-amine) hydrochloride is an E3 ligase ligand-linker conjugate. Pomalidomide-C7-NH2 hydrochloride can be used for the synthesis of PROTAC[1][2].

Name	Pomalidomide 4'-alkylC7-amine
Synonym	More Synonyms

Description	Pomalidomide-C7-NH2 (Pomalidomide 4'-alkylC7-amine) hydrochloride is an E3 ligase ligand-linker conjugate. Pomalidomide-C7-NH2 hydrochloride can be used for the synthesis of PROTAC[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
References	[1]. Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 2019 Jan 24;62(2):448-466. [2]. Si Woo Choi, et al. Hmg-coa reductase degradation inducing compound. Patent, WO2021201577A1.

Description

Pomalidomide-C7-NH2 (Pomalidomide 4'-alkylC7-amine) hydrochloride is an E3 ligase ligand-linker conjugate. Pomalidomide-C7-NH2 hydrochloride can be used for the synthesis of PROTAC[1][2].

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

References

[1]. Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 2019 Jan 24;62(2):448-466.

[2]. Si Woo Choi, et al. Hmg-coa reductase degradation inducing compound. Patent, WO2021201577A1.

Molecular Formula	C₂₀H₂₇ClN₄O₄
Molecular Weight	422.91
Exact Mass	422.172089

1H-Isoindole-1,3(2H)-dione, 4-[(7-aminoheptyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1)

4-[(7-Aminoheptyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride

4-[(7-Aminoheptyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride (1:1)

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Pomalidomide-C7-NH2 hydrochloride

Use of Pomalidomide-C7-NH2 hydrochloride

Names

Pomalidomide-C7-NH2 hydrochloride Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.