Ormutivimab

Modify Date: 2025-08-25 15:18:46

Ormutivimab Structure
Ormutivimab structure
Common Name Ormutivimab
CAS Number 2449086-91-1 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ormutivimab


Ormutivimab (rhRIG) is a recombinant human monoclonal antibody, targeting rabies virus. Ormutivimab neutralizes a variety of rabies virus strains. Ormutivimab exhibits potent potency against rabies post-exposure prophylaxis (PEP) model[1][2].

 Names

Name Ormutivimab

 Ormutivimab Biological Activity

Description Ormutivimab (rhRIG) is a recombinant human monoclonal antibody, targeting rabies virus. Ormutivimab neutralizes a variety of rabies virus strains. Ormutivimab exhibits potent potency against rabies post-exposure prophylaxis (PEP) model[1][2].
Related Catalog
In Vivo Ormutivimab (20 IU/kg;肌肉注射;单剂量) 保护比格犬免受 RABV BD06 的致命攻击[1]。 Ormutivimab (20 IU/kg、100 IU/kg;肌注;单剂量) 保护受攻击的 Kunming 小鼠免受各种狂犬病病毒的侵害[1]。 Animal Model: Balb/c mice challenge model with rabies virus[1] Dosage: 20 IU/kg, 100 IU/kg Administration: Intramuscular injection; single dose after 4 hr after infection Result: Protected mice from rabies CVS-24 and GZ-1 isolates at a comparable rate (90%) to that of HRIG, human antirabies immune globulin.
References

[1]. Zhai LL, et al. Efficacy of ormutivimab, a novel recombinant human anti-rabies monoclonal antibody, in post-exposure prophylaxis animal models. Travel Med Infect Dis. 2022 Mar-Apr;46:102267.  

[2]. Zhang J, et al. Population Pharmacodynamic Analyses of Human Anti-Rabies Virus Monoclonal Antibody (Ormutivimab) in Healthy Adult Subjects. Vaccines (Basel). 2022 Jul 29;10(8):1218.  

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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