GAD65 (206-220)

Modify Date: 2025-08-22 09:08:20

GAD65 (206-220) Structure
GAD65 (206-220) structure
Common Name GAD65 (206-220)
CAS Number 245124-26-9 Molecular Weight 1757.03
Density N/A Boiling Point N/A
Molecular Formula C86H129N15O24 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GAD65 (206-220)


GAD65 (206-220) is glutamic acid decarboxylase (GAD) 65-derived peptide, corresponding to residues 180-188. GAD65 is presented to T cells in association with I-Ag7 MHC class II molecules and a major pancreatic antigens targeted by self-reactive T cells in type I diabetes mellitus[1].

 Names

Name GAD65 (206-220)

 GAD65 (206-220) Biological Activity

Description GAD65 (206-220) is glutamic acid decarboxylase (GAD) 65-derived peptide, corresponding to residues 180-188. GAD65 is presented to T cells in association with I-Ag7 MHC class II molecules and a major pancreatic antigens targeted by self-reactive T cells in type I diabetes mellitus[1].
Related Catalog
References

[1]. Seon-Kyeong Kim, et al. Prevention of type I diabetes transfer by glutamic acid decarboxylase 65 peptide 206-220-specific T cells. Proc Natl Acad Sci U S A

 Chemical & Physical Properties

Molecular Formula C86H129N15O24
Molecular Weight 1757.03
InChIKey OFOCKFGJFKKSKN-UOSQTKIHSA-N
SMILES CCC(C)C(NC(=O)C(CCC(=O)O)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(N)C(C)O)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(C(=O)NC(Cc1ccccc1)C(=O)NC(C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(C(=O)NC(C(=O)O)C(C)O)C(C)C)C(C)C)C(C)C
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