EtDO-P4

Modify Date: 2024-01-06 16:00:10

EtDO-P4 Structure
EtDO-P4 structure
Common Name EtDO-P4
CAS Number 245329-78-6 Molecular Weight 516.75600
Density 1.05g/cm3 Boiling Point 684.419ºC at 760 mmHg
Molecular Formula C31H52N2O4 Melting Point N/A
MSDS N/A Flash Point 367.723ºC

 Use of EtDO-P4


EtDO-P4 is a nanomolar inhibitor of glycosphingolipid (GSL) synthesis. EtDO-P4 suppresses activation of the EGFR-induced ERK pathway and various receptor tyrosine kinases (RTKs). EtDO-P4 can be used for various types of cancer, including Burkitt’s lymphoma[1].

 Names

Name N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]hexadecanamide
Synonym More Synonyms

 EtDO-P4 Biological Activity

Description EtDO-P4 is a nanomolar inhibitor of glycosphingolipid (GSL) synthesis. EtDO-P4 suppresses activation of the EGFR-induced ERK pathway and various receptor tyrosine kinases (RTKs). EtDO-P4 can be used for various types of cancer, including Burkitt’s lymphoma[1].
Related Catalog
References

[1]. Seung-Yeol Park, et al. Globoside promotes activation of ERK by interaction with the epidermal growth factor receptor. Biochim Biophys Acta. 2012 Jul;1820(7):1141-8.

 Chemical & Physical Properties

Density 1.05g/cm3
Boiling Point 684.419ºC at 760 mmHg
Molecular Formula C31H52N2O4
Molecular Weight 516.75600
Flash Point 367.723ºC
Exact Mass 516.39300
PSA 71.03000
LogP 6.88190
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.524

 Synonyms

D-threo-1-(3',4'-Ethylenedioxy)phenyl-2-palmitoylamino-3-pyrrolidino-1-propanol
Hexadecanamide,N-[(1R,2R)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]