Lamotrigine-13C2,15N

Modify Date: 2024-01-08 14:37:23

Lamotrigine-13C2,15N structure	Common Name	Lamotrigine-13C2,15N
	CAS Number	2483830-10-8	Molecular Weight	259.07
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₇₁₃C₂H₇Cl₂N₄₁₅N	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Lamotrigine-13C2,15N

Lamotrigine-13C2,15N is the 13C and 15N labeled Lamotrigine[1]. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy,?focal seizure, et al[2][3].

Name	Lamotrigine-13C2,15N

Description	Lamotrigine-13C2,15N is the 13C and 15N labeled Lamotrigine[1]. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy,?focal seizure, et al[2][3].
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In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. M J Leach, et al. Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action. Epilepsia. Sep-Oct 1986;27(5):490-7. [3]. Damianka P Getova, et al. A study of the effects of lamotrigine on mice using two convulsive tests. Folia Med (Plovdiv). Apr-Jun 201153(2):57-62.

Molecular Formula	C₇₁₃C₂H₇Cl₂N₄₁₅N
Molecular Weight	259.07

Lamotrigine-13C2,15N

Use of Lamotrigine-13C2,15N

Names

Lamotrigine-13C2,15N Biological Activity

Chemical & Physical Properties