Uracil-d1-1

Modify Date: 2024-01-08 03:02:32

Uracil-d1-1 Structure
Uracil-d1-1 structure
Common Name Uracil-d1-1
CAS Number 24897-51-6 Molecular Weight 113.09300
Density 1.333 g/cm3 Boiling Point N/A
Molecular Formula C4H3DN2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Uracil-d1-1


Uracil-d1-1 is the deuterium labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].

 Names

Name uracil-6-d1
Synonym More Synonyms

 Uracil-d1-1 Biological Activity

Description Uracil-d1-1 is the deuterium labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Pałasz A, et al. In search of uracil derivatives as bioactive agents. Uracils and fused uracils: Synthesis, biological activity and applications. Eur J Med Chem. 2015 Jun 5;97:582-611.  

 Chemical & Physical Properties

Density 1.333 g/cm3
Molecular Formula C4H3DN2O2
Molecular Weight 113.09300
Exact Mass 113.03400
PSA 65.72000

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

6-deuterio-1H-pyrimidine-2,4-dione
<6-14C>-Glucose
Glucose-6-14C
D-Glucose-6-14C