α-Synuclein inhibitor 5

Modify Date: 2024-01-21 19:19:01

α-Synuclein inhibitor 5 Structure
α-Synuclein inhibitor 5 structure
Common Name α-Synuclein inhibitor 5
CAS Number 2489813-11-6 Molecular Weight 414.43
Density N/A Boiling Point N/A
Molecular Formula C20H18N2O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of α-Synuclein inhibitor 5


α-Synuclein inhibitor 5 (compound 4aa) is a potent and BBB-penetrated inhibitor of α-Synuclein (α-Syn) aggregation, with an IC50 of 1.22 μM and inhibition ratio at 30 μM of 94.3%[1].

 Names

Name α-Synuclein inhibitor 5

 α-Synuclein inhibitor 5 Biological Activity

Description α-Synuclein inhibitor 5 (compound 4aa) is a potent and BBB-penetrated inhibitor of α-Synuclein (α-Syn) aggregation, with an IC50 of 1.22 μM and inhibition ratio at 30 μM of 94.3%[1].
Related Catalog
Target

IC50: 1.22 ± 0.14 μM (α-Synuclein)[1]

References

[1]. Chen L, et al. Amide derivatives of Gallic acid: Design, synthesis and evaluation of inhibitory activities against in vitro α-synuclein aggregation. Bioorg Med Chem. 2020 Aug 1;28(15):115596.

 Chemical & Physical Properties

Molecular Formula C20H18N2O6S
Molecular Weight 414.43