AXC-715 hydrochloride

Modify Date: 2024-01-13 09:42:10

AXC-715 hydrochloride Structure
AXC-715 hydrochloride structure
Common Name AXC-715 hydrochloride
CAS Number 2490497-93-1 Molecular Weight 347.89
Density N/A Boiling Point N/A
Molecular Formula C18H26ClN5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AXC-715 hydrochloride


AXC-715 hydrochloride is a TLR7/TLR8 dual agonist, extracted from patent WO2020168017 A1[1]. AXC-715, compound D from WO2020190734A1, can be used for synthesis of antibody-adjuvant immunoconjugates, comprising an antibody construct that binds programmed death-ligand 1 (PD-L1) linked to one or more adjuvants[2].

 Names

Name AXC-715 hydrochloride

 AXC-715 hydrochloride Biological Activity

Description AXC-715 hydrochloride is a TLR7/TLR8 dual agonist, extracted from patent WO2020168017 A1[1]. AXC-715, compound D from WO2020190734A1, can be used for synthesis of antibody-adjuvant immunoconjugates, comprising an antibody construct that binds programmed death-ligand 1 (PD-L1) linked to one or more adjuvants[2].
Related Catalog
Target

TLR8

TLR7

References

[1]. Sung-Ju Moon, et al. Compositions containing, methods and uses of antibody-tlr agonist conjugates. Patent WO2020168017A1

[2]. Shelley Erin ACKERMAN, et al. Immunoconjugates targeting pd-l1. Patent WO2020190734A1.

 Chemical & Physical Properties

Molecular Formula C18H26ClN5
Molecular Weight 347.89