2,5-Cyclohexadiene-1,4-dione,2,5-bis(4-ethylphenyl)-3,6-dihydroxy
Modify Date: 2026-07-01 14:48:31
2,5-Cyclohexadiene-1,4-dione,2,5-bis(4-ethylphenyl)-3,6-dihydroxy structure
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Common Name | 2,5-Cyclohexadiene-1,4-dione,2,5-bis(4-ethylphenyl)-3,6-dihydroxy | ||
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| CAS Number | 24909-18-0 | Molecular Weight | 348.39200 | |
| Density | 1.309g/cm3 | Boiling Point | 555.2ºC at 760 mmHg | |
| Molecular Formula | C22H20O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 303.7ºC | |
Use of 2,5-Cyclohexadiene-1,4-dione,2,5-bis(4-ethylphenyl)-3,6-dihydroxyNSC114126 is a potent and orally active inhibitor of EGFR tyrosine kinase (EGFR-TK). NSC114126 has strong antiproliferative activities. NSC114126 has the potential for the research of cancer diseases[1]. |
| Name | 2,5-bis(4-ethylphenyl)-3,6-dihydroxycyclohexa-2,5-diene-1,4-dione |
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| Synonym | More Synonyms |
| Description | NSC114126 is a potent and orally active inhibitor of EGFR tyrosine kinase (EGFR-TK). NSC114126 has strong antiproliferative activities. NSC114126 has the potential for the research of cancer diseases[1]. |
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| Related Catalog | |
| References |
| Density | 1.309g/cm3 |
|---|---|
| Boiling Point | 555.2ºC at 760 mmHg |
| Molecular Formula | C22H20O4 |
| Molecular Weight | 348.39200 |
| Flash Point | 303.7ºC |
| Exact Mass | 348.13600 |
| PSA | 74.60000 |
| LogP | 4.20160 |
| Vapour Pressure | 3.66E-13mmHg at 25°C |
| Index of Refraction | 1.66 |
| InChIKey | JTTAVDAEVCLLLX-UHFFFAOYSA-N |
| SMILES | CCc1ccc(C2=C(O)C(=O)C(c3ccc(CC)cc3)=C(O)C2=O)cc1 |
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2,5-Cyclohexadi... CAS#:24909-18-0 |
| Literature: Zee-Cheng,K.-Y.; Cheng,C.C. Journal of Medicinal Chemistry, 1970 , vol. 13, p. 264 - 268 |
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~%
2,5-Cyclohexadi... CAS#:24909-18-0 |
| Literature: Zee-Cheng,K.-Y.; Cheng,C.C. Journal of Medicinal Chemistry, 1970 , vol. 13, p. 264 - 268 |
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~%
2,5-Cyclohexadi... CAS#:24909-18-0 |
| Literature: Zee-Cheng,K.-Y.; Cheng,C.C. Journal of Medicinal Chemistry, 1970 , vol. 13, p. 264 - 268 |
| Precursor 3 | |
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| DownStream 0 | |
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Name: Antiproliferative activity against human A-431 cells overexpressing EGFR assessed as ...
Source: ChEMBL
Target: A-431
External Id: CHEMBL5133514
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Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose
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Name: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell...
Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose
|
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| 2,5-Bis-(p-ethylphenyl)-3,6-dihydroxy-p-benzochinon |
| p-Benzoquinone,2,5-bis(p-ethylphenyl)-3,6-dihydroxy |