EGFR/BRAFV600E-IN-1
Modify Date: 2026-07-28 19:38:26
EGFR/BRAFV600E-IN-1 structure
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Common Name | EGFR/BRAFV600E-IN-1 | ||
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| CAS Number | 2492429-45-3 | Molecular Weight | 437.92 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H24ClN3O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of EGFR/BRAFV600E-IN-1EGFR/BRAFV600E-IN-1 (Compound 23) is a potent EGFR and BRAFV600E dual inhibitor with IC50s of 0.08 and 0.15 µM, respectively. EGFR/BRAFV600E-IN-1 induces apoptosis and cell cycle arrest in both pre-G1 and G2/M phases. EGFR/BRAFV600E-IN-1 exhibits antiproliferative activity againist A-549, MCF-7, Panc-1, HT-29 with IC50s of 1.2, 0.79, 1.3, and 1.23 µM, respectively[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | EGFR/BRAFV600E-IN-1 |
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This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | EGFR/BRAFV600E-IN-1 (Compound 23) is a potent EGFR and BRAFV600E dual inhibitor with IC50s of 0.08 and 0.15 µM, respectively. EGFR/BRAFV600E-IN-1 induces apoptosis and cell cycle arrest in both pre-G1 and G2/M phases. EGFR/BRAFV600E-IN-1 exhibits antiproliferative activity againist A-549, MCF-7, Panc-1, HT-29 with IC50s of 1.2, 0.79, 1.3, and 1.23 µM, respectively[1]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C24H24ClN3O3 |
|---|---|
| Molecular Weight | 437.92 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the uses of EGFR/BRAFV600E-IN-1? |
| A: Main uses of EGFR/BRAFV600E-IN-1: EGFR/BRAFV600E-IN-1 (Compound 23) is a potent EGFR and BRAFV600E dual inhibitor with IC50s of 0.08 and 0.15 µM, respectively. EGFR/BRAFV600E-IN-1 induces apoptosis and cell cycle arrest in both pre-G1 and G2/M phases. EGFR/BRAFV600E-IN-1 exhibits antiproliferative activity againist A-549, MCF-7, Panc-1, HT-29 with IC50s of 1.2, 0.79, 1.3, and 1.23 µM, respectively[1]. |
| Q: What is the molecular weight of EGFR/BRAFV600E-IN-1? |
| A: Molecular weight of EGFR/BRAFV600E-IN-1 is 437.92. |
| Q: What is the English name of EGFR/BRAFV600E-IN-1? |
| A: The English name of EGFR/BRAFV600E-IN-1 is EGFR/BRAFV600E-IN-1. |
| Q: What is the Chinese name of 2492429-45-3? |
| A: Chinese name of 2492429-45-3 is 2492429-45-3. |
| Q: What is the CAS number of EGFR/BRAFV600E-IN-1? |
| A: CAS number of EGFR/BRAFV600E-IN-1 is 2492429-45-3. |
| Q: What is the molecular formula of EGFR/BRAFV600E-IN-1? |
| A: Molecular formula of EGFR/BRAFV600E-IN-1 is C24H24ClN3O3. |