7-(tert-Butyl)-6-chloro-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine

Modify Date: 2024-01-10 08:36:19

7-(tert-Butyl)-6-chloro-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine Structure
7-(tert-Butyl)-6-chloro-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine structure
Common Name 7-(tert-Butyl)-6-chloro-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine
CAS Number 252977-54-1 Molecular Weight 304.75000
Density N/A Boiling Point N/A
Molecular Formula C15H14ClFN4 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 7-tert-butyl-6-chloro-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C15H14ClFN4
Molecular Weight 304.75000
Exact Mass 304.08900
PSA 43.08000
LogP 3.88130
Storage condition 2-8°C

 Synthetic Route

~44%

7-(tert-Butyl)-6-chloro-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine Structure

7-(tert-Butyl)-...

CAS#:252977-54-1

Literature: Merck Sharp and Dohme Ltd. Patent: US6630471 B1, 2003 ;

~69%

7-(tert-Butyl)-6-chloro-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine Structure

7-(tert-Butyl)-...

CAS#:252977-54-1

Literature: Merck Sharp and Dohme Ltd. Patent: US6630471 B1, 2003 ;

~44%

7-(tert-Butyl)-6-chloro-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine Structure

7-(tert-Butyl)-...

CAS#:252977-54-1

Literature: Carling, Robert W.; Madin, Andrew; Guiblin, Alec; Russell, Michael G. N.; Moore, Kevin W.; Mitchinson, Andrew; Sohal, Bindi; Pike, Andrew; Cook, Susan M.; Ragan, Ian C.; McKernan, Ruth M.; Quirk, Kathleen; Ferris, Pushpinder; Marshall, George; Thompson, Sally Ann; Wafford, Keith A.; Dawson, Gerard R.; Atack, John R.; Harrison, Timothy; Castro, Jose L.; Street, Leslie J. Journal of Medicinal Chemistry, 2005 , vol. 48, # 23 p. 7089 - 7092

 Synonyms

6-chloro-7-(1,1-dimethylethyl)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine
QC-4197
6-chloro-7-(1,1-dimethyleth-1-yl)-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine