252977-54-1

252977-54-1 structure

Name: 7-(tert-Butyl)-6-chloro-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine
Chemical Name: 7-tert-butyl-6-chloro-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine
CAS Number: 252977-54-1
Molecular Formula: C₁₅H₁₄ClFN₄
Molecular Weight: 304.75000
Create Date: 2017-04-02 16:04:15
Modify Date: 2024-01-10 08:36:19

Name	7-tert-butyl-6-chloro-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine
Synonyms	6-chloro-7-(1,1-dimethylethyl)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine QC-4197 6-chloro-7-(1,1-dimethyleth-1-yl)-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine

Molecular Formula	C₁₅H₁₄ClFN₄
Molecular Weight	304.75000
Exact Mass	304.08900
PSA	43.08000
LogP	3.88130
Storage condition	2-8°C

22808-29-3

446-24-2

~44%

252977-54-1

Literature: Merck Sharp and Dohme Ltd. Patent: US6630471 B1, 2003 ;

252977-55-2

393-52-2

~69%

252977-54-1

Literature: Merck Sharp and Dohme Ltd. Patent: US6630471 B1, 2003 ;

22808-29-3

51859-98-4

~44%

252977-54-1

Literature: Carling, Robert W.; Madin, Andrew; Guiblin, Alec; Russell, Michael G. N.; Moore, Kevin W.; Mitchinson, Andrew; Sohal, Bindi; Pike, Andrew; Cook, Susan M.; Ragan, Ian C.; McKernan, Ruth M.; Quirk, Kathleen; Ferris, Pushpinder; Marshall, George; Thompson, Sally Ann; Wafford, Keith A.; Dawson, Gerard R.; Atack, John R.; Harrison, Timothy; Castro, Jose L.; Street, Leslie J. Journal of Medicinal Chemistry, 2005 , vol. 48, # 23 p. 7089 - 7092

Precursor 5
22808-29-3 446-24-2 252977-55-2 393-52-2
51859-98-4
DownStream 0

1158522-08-7	940364-43-2
446843-04-5	134104-43-1
131615-57-1	955668-90-3
6906-52-1	930439-75-1
1018584-77-4	1375289-11-4