Dimethylmatairesinol

Modify Date: 2025-08-23 16:31:07

Dimethylmatairesinol Structure
Dimethylmatairesinol structure
Common Name Dimethylmatairesinol
CAS Number 25488-59-9 Molecular Weight 386.44
Density 1.2±0.1 g/cm3 Boiling Point 545.6±45.0 °C at 760 mmHg
Molecular Formula C22H26O6 Melting Point N/A
MSDS N/A Flash Point 237.2±28.8 °C

 Use of Dimethylmatairesinol


Dimethylmatairesinol (compound 8) is a lignan compound isolated from the seed of Hernandia nymphaeifolia. Dimethylmatairesinol shows cytotoxicity against the KKU-M156 and HepG2 cell line with IC50s of 5.4 μM (Emax 59%) and 5.2 μM (Emax 78%), respectively[1].

 Names

Name Dimethylmatairesinol
Synonym More Synonyms

 Dimethylmatairesinol Biological Activity

Description Dimethylmatairesinol (compound 8) is a lignan compound isolated from the seed of Hernandia nymphaeifolia. Dimethylmatairesinol shows cytotoxicity against the KKU-M156 and HepG2 cell line with IC50s of 5.4 μM (Emax 59%) and 5.2 μM (Emax 78%), respectively[1].
Related Catalog
References

[1]. Jittra Suthiwong, et al. Cytotoxicity against Cholangiocarcinoma and HepG2 Cell Lines of Lignans from Hernandia nymphaeifolia.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 545.6±45.0 °C at 760 mmHg
Molecular Formula C22H26O6
Molecular Weight 386.44
Flash Point 237.2±28.8 °C
Exact Mass 386.172943
PSA 63.22000
LogP 3.23
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.553
InChIKey SNAOLIMFHAAIER-DLBZAZTESA-N
SMILES COc1ccc(CC2COC(=O)C2Cc2ccc(OC)c(OC)c2)cc1OC

 Safety Information

Hazard Codes Xi
HS Code 2932209090

 Customs

HS Code 2932209090
Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 DimethylmatairesinolBioassay

View more

Name: Ratio of glucose uptake in rat L6 cells at 3 uM after 2 hrs to glucose uptake in rat ...
Source: ChEMBL
Target: L6
External Id: CHEMBL3578876
Name: Cytotoxicity against Wistar rat peritoneal macrophages assessed as lysosomal activity...
Source: ChEMBL
Target: Peritoneal macrophage
External Id: CHEMBL4672029
Name: Cytotoxicity against Aedes albopictus NIAS-AeAl-2 cells assessed as reduction in cell...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4623565
Name: Increase in glucose uptake in rat L6 cells at 3 uM pre-treated with compound for 30 m...
Source: ChEMBL
Target: L6
External Id: CHEMBL3578866
Name: Antimicrobial activity against Neisseria gonorrhoeae ATCC 49226 by antimicrobial susc...
Source: ChEMBL
Target: Neisseria gonorrhoeae
External Id: CHEMBL1036073
Name: Cytotoxicity against Spodoptera frugiperda Sf9 cells assessed as reduction in cell vi...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4623567
Name: Increase in glucose uptake in rat L6 cells at 3 uM pre-treated with compound for 30 m...
Source: ChEMBL
Target: L6
External Id: CHEMBL3578871
Name: Cytotoxicity against Wistar rat splenocytes assessed as lysosomal activity at 100 uM ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4672022
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 Synonyms

(3R,4R)-3,4-Bis(3,4-dimethoxybenzyl)dihydro-2(3H)-furanone
Methylarctigenin
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