1,2-Diphenylethanamine

Modify Date: 2024-01-01 17:51:19

1,2-Diphenylethanamine Structure
1,2-Diphenylethanamine structure
Common Name 1,2-Diphenylethanamine
CAS Number 25611-78-3 Molecular Weight 197.276
Density 1.1±0.1 g/cm3 Boiling Point 311.1±0.0 °C at 760 mmHg
Molecular Formula C14H15N Melting Point N/A
MSDS Chinese USA Flash Point 136.8±10.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 1,2-diphenylethanamine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 311.1±0.0 °C at 760 mmHg
Molecular Formula C14H15N
Molecular Weight 197.276
Flash Point 136.8±10.9 °C
Exact Mass 197.120453
PSA 26.02000
LogP 3.13
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.597

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SI2299000
CHEMICAL NAME :
Phenethylamine, alpha-phenyl-
CAS REGISTRY NUMBER :
25611-78-3
LAST UPDATED :
199206
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C14-H15-N
MOLECULAR WEIGHT :
197.30
WISWESSER LINE NOTATION :
ZYR&1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHBUA9 Pharmaceutical Bulletin. (Tokyo, Japan) V.1-5, 1953-57. For publisher information, see CPBTAL. Volume(issue)/page/year: 1,174,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
145 mg/kg
TOXIC EFFECTS :
Behavioral - food intake (animal) Behavioral - changes in motor activity (specific assay)
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 28,1561,1978

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS SI2299000
HS Code 2921499090

 Synthetic Route

 Customs

HS Code 2921499090
Summary 2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles3

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Lefetamine, a controlled drug and pharmaceutical lead of new designer drugs: synthesis, metabolism, and detectability in urine and human liver preparations using GC-MS, LC-MS(n), and LC-high resolution-MS/MS.

Anal. Bioanal. Chem 407(6) , 1545-57, (2015)

Lefetamine (N,N-dimethyl-1,2-diphenylethylamine, L-SPA) was marketed as an opioid analgesic in Japan and Italy. After being widely abused, it became a controlled substance. It seems to be a pharmaceut...

Superficially porous particles vs. fully porous particles for bonded high performance liquid chromatographic chiral stationary phases: isopropyl cyclofructan 6.

J. Chromatogr. A. 1363 , 89-95, (2014)

This work reports a comparison of HPLC separations of enantiomers with chiral stationary phases (CSPs) prepared by chemically bonding cyclofructan-6, functionalized with isopropyl carbamate groups on ...

NMDA receptor affinities of 1,2-diphenylethylamine and 1-(1,2-diphenylethyl)piperidine enantiomers and of related compounds.

Bioorg. Med. Chem. 17 , 3456-62, (2009)

We resolved 1,2-diphenylethylamine (DPEA) into its (S)- and (R)-enantiomer and used them as precursors for synthesis of (S)- and (R)-1-(1,2-diphenylethyl)piperidine, flexible homeomorphs of the NMDA c...

 Synonyms

1-Amino-1,2-diphenylethane
EINECS 247-126-4
1,2-DiphenylethylaMine
MFCD00008063
α-Benzylbenzylamine
1,2-diphenylethan-1-amine
1,2-Diphenylethanamine
Benzeneethanamine, α-phenyl-