KSK68

Modify Date: 2024-01-28 10:51:42

KSK68 structure	Common Name	KSK68
	CAS Number	2566715-91-9	Molecular Weight	364.48
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₈N₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of KSK68

KSK68 is a high-affinity dual sigma-1 and histamine H3 receptor antagonist, with Kis of 7.7, 3.6, 22.4 nM for H3 receptor, sigma-1, sigma-2 receptor respectively. KSK68 has negligible affinity at the other histamine receptor subtypes. KSK68 can be used for research of nociceptive and neuropathic pain[1].

Name	KSK68

Description	KSK68 is a high-affinity dual sigma-1 and histamine H3 receptor antagonist, with Kis of 7.7, 3.6, 22.4 nM for H3 receptor, sigma-1, sigma-2 receptor respectively. KSK68 has negligible affinity at the other histamine receptor subtypes. KSK68 can be used for research of nociceptive and neuropathic pain[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Sigma Receptor Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
Target	7.7 nM, 3.6 nM、22.4 nM (H3 receptor, sigma-1, sigma-2 receptor)[1]
References	[1]. Szczepańska K, et al. Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain. J Med Chem. 2023 Jul 27;66(14):9658-9683.

Molecular Formula	C₂₃H₂₈N₂O₂
Molecular Weight	364.48

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: KSK68
Price: Check
Purity: 97.22%
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Contact: Yang
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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.