(4R)-4-{[tert-Butyl(diphenyl)silyl]oxy}-L-proline

Modify Date: 2024-01-09 18:48:55

(4R)-4-{[tert-Butyl(diphenyl)silyl]oxy}-L-proline Structure
(4R)-4-{[tert-Butyl(diphenyl)silyl]oxy}-L-proline structure
Common Name (4R)-4-{[tert-Butyl(diphenyl)silyl]oxy}-L-proline
CAS Number 259212-61-8 Molecular Weight 369.530
Density 1.1±0.1 g/cm3 Boiling Point 468.8±45.0 °C at 760 mmHg
Molecular Formula C21H27NO3Si Melting Point 198 °C(dec.)
MSDS N/A Flash Point 237.3±28.7 °C

 Names

Name (2S,4R)-4-[tert-butyl(diphenyl)silyl]oxypyrrolidine-2-carboxylic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 468.8±45.0 °C at 760 mmHg
Melting Point 198 °C(dec.)
Molecular Formula C21H27NO3Si
Molecular Weight 369.530
Flash Point 237.3±28.7 °C
Exact Mass 369.176025
PSA 58.56000
LogP 5.23
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.574

 Synthetic Route

~98%

(4R)-4-{[tert-Butyl(diphenyl)silyl]oxy}-L-proline Structure

(4R)-4-{[tert-B...

CAS#:259212-61-8

Literature: Freund, Matthias H.; Tsogoeva, Svetlana B. Synlett, 2011 , # 4 p. 503 - 507

~98%

(4R)-4-{[tert-Butyl(diphenyl)silyl]oxy}-L-proline Structure

(4R)-4-{[tert-B...

CAS#:259212-61-8

Literature: Delaney, Joshua P.; Brozinski, Hannah L.; Henderson, Luke C. Organic and Biomolecular Chemistry, 2013 , vol. 11, # 18 p. 2951 - 2960

~%

(4R)-4-{[tert-Butyl(diphenyl)silyl]oxy}-L-proline Structure

(4R)-4-{[tert-B...

CAS#:259212-61-8

Literature: Organic Letters, , vol. 7, # 19 p. 4185 - 4188

~%

(4R)-4-{[tert-Butyl(diphenyl)silyl]oxy}-L-proline Structure

(4R)-4-{[tert-B...

CAS#:259212-61-8

Literature: Organic Letters, , vol. 7, # 19 p. 4185 - 4188

~73%

(4R)-4-{[tert-Butyl(diphenyl)silyl]oxy}-L-proline Structure

(4R)-4-{[tert-B...

CAS#:259212-61-8

Literature: Opalka, Suzanne M.; Steinbacher, Jeremy L.; Lambiris, Brandon A.; McQuade, D. Tyler Journal of Organic Chemistry, 2011 , vol. 76, # 16 p. 6503 - 6517

~%

(4R)-4-{[tert-Butyl(diphenyl)silyl]oxy}-L-proline Structure

(4R)-4-{[tert-B...

CAS#:259212-61-8

Literature: Synlett, , # 4 p. 503 - 507

~%

(4R)-4-{[tert-Butyl(diphenyl)silyl]oxy}-L-proline Structure

(4R)-4-{[tert-B...

CAS#:259212-61-8

Literature: Synlett, , # 4 p. 503 - 507

 Synonyms

(4R)-4-{[tert-Butyl(diphenyl)silyl]oxy}-L-proline
L-4-(tert-butyldiphenylsilyloxy)proline
(2S,4R)-4-(tert-Butyldiphenylsilyloxy)pyrrolidine-2-carboxylic Acid
B3440
(4R)-4-(t-butyldiphenylsilyloxy)-L-proline
trans-4-tertbutlydiphenylsiloxy-L-proline
(4R)-4-(tert-butyldiphenylsiloxy)-L-proline
O-TBDPS-proline
(4R)-4-{[(2-Methyl-2-propanyl)(diphenyl)silyl]oxy}-L-proline
L-Proline, 4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-, (4R)-
trans-4-(tert-Butyldiphenylsilyloxy)-L-proline
4-(tert-butyldiphenylsilyloxy)-pyrrolidine-2-carboxylic acid
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