Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium

Modify Date: 2025-08-27 16:02:56

Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium Structure
Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium structure
 Common Name Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium
CAS Number 2611373-74-9 Molecular Weight 626.84
Density N/A Boiling Point N/A
Molecular Formula C29H55N6O5PSi Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium


Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) exhibits substantially longer t1/2 values than tenofovir in human liver microsomes, potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo.

 Names

Name Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium

  Biological Activity

Description Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) exhibits substantially longer t1/2 values than tenofovir in human liver microsomes, potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo.
Related Catalog
References

[1]. Pribut N, et al. ω-Functionalized Lipid Prodrugs of HIV NtRTI Tenofovir with Enhanced Pharmacokinetic Properties. J Med Chem. 2021 Sep 9;64(17):12917-12937.

 Chemical & Physical Properties

Molecular Formula C29H55N6O5PSi
Molecular Weight 626.84
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Chemsrc provides CAS#:2611373-74-9 MSDS, density, melting point, boiling point, structure, etc. Its name is Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium>> amp version: Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium

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