Tenofovir-C3-O-C15-CF3 ammonium

Modify Date: 2025-08-27 14:30:18

Tenofovir-C3-O-C15-CF3 ammonium Structure
Tenofovir-C3-O-C15-CF3 ammonium structure
 Common Name Tenofovir-C3-O-C15-CF3 ammonium
CAS Number 2611373-80-7 Molecular Weight 640.72
Density N/A Boiling Point N/A
Molecular Formula C28H52F3N6O5P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tenofovir-C3-O-C15-CF3 ammonium


Tenofovir-C3-O-C15-CF3 (ammonium) exhibits substantially longer t1/2 values than tenofovir in human liver microsomes, potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo.

 Names

Name Tenofovir-C3-O-C15-CF3 ammonium

 Tenofovir-C3-O-C15-CF3 ammonium Biological Activity

Description Tenofovir-C3-O-C15-CF3 (ammonium) exhibits substantially longer t1/2 values than tenofovir in human liver microsomes, potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo.
Related Catalog
References

[1]. Pribut N, et al. ω-Functionalized Lipid Prodrugs of HIV NtRTI Tenofovir with Enhanced Pharmacokinetic Properties. J Med Chem. 2021 Sep 9;64(17):12917-12937.

 Chemical & Physical Properties

Molecular Formula C28H52F3N6O5P
Molecular Weight 640.72
InChIKey MAVYHINXUMVIRW-GJFSDDNBSA-N
SMILES CC(Cn1cnc2c(N)ncnc21)OCP(=O)(O)OCCCOCCCCCCCCCCCCCCCC(F)(F)F.N
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