Glycine,N-formyl-N-hydroxy-, monosodium salt (8CI,9CI)

Modify Date: 2024-01-02 00:38:29

Glycine,N-formyl-N-hydroxy-, monosodium salt (8CI,9CI) Structure
Glycine,N-formyl-N-hydroxy-, monosodium salt (8CI,9CI) structure
Common Name Glycine,N-formyl-N-hydroxy-, monosodium salt (8CI,9CI)
CAS Number 2618-22-6 Molecular Weight 142.06600
Density 1.592g/cm3 Boiling Point 367.1ºC at 760mmHg
Molecular Formula C3H5NNaO4+ Melting Point N/A
MSDS N/A Flash Point 175.8ºC

 Names

Name sodium,2-[formyl(hydroxy)amino]acetate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.592g/cm3
Boiling Point 367.1ºC at 760mmHg
Molecular Formula C3H5NNaO4+
Molecular Weight 142.06600
Flash Point 175.8ºC
Exact Mass 142.01200
PSA 77.84000
Vapour Pressure 7.03E-07mmHg at 25°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MC0555000
CHEMICAL NAME :
Glycine, N-formyl-N-hydroxy-, sodium salt
CAS REGISTRY NUMBER :
2618-22-6
LAST UPDATED :
198910
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C3-H4-N-O4.Na
MOLECULAR WEIGHT :
141.07

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
1176 mg/kg
SEX/DURATION :
female 9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
1764 mg/kg
SEX/DURATION :
female 8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
1764 mg/kg
SEX/DURATION :
female 11 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - mouse Embryo
DOSE/DURATION :
4 gm/L/2D
REFERENCE :
ECEBDI Experimental Cell Biology. (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.44- 1976- Volume(issue)/page/year: 46,152,1978

 Synthetic Route

~82%

Glycine,N-formyl-N-hydroxy-, monosodium salt (8CI,9CI) Structure

Glycine,N-formy...

CAS#:2618-22-6

Literature: Yazawa, Hisatoyo; Goto, Shunsuke Tetrahedron Letters, 1985 , vol. 26, # 31 p. 3703 - 3706

~%

Glycine,N-formyl-N-hydroxy-, monosodium salt (8CI,9CI) Structure

Glycine,N-formy...

CAS#:2618-22-6

Literature: Goto; Kawakita; Okutani; Miki Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 8 p. 3202 - 3207

 Synonyms

N-Formylhydroxyaminoessigsaeure-natrium
Hadacidin sodium salt
N-formyl-N-hydroxyglycine Na salt
Hedacidin
Sodium N-hydroxy-N-formylglycinate
Sodium hadacidin
Hadacidin sodium
hadacidine monosodium salt
Hadacidin monosodium salt
Amchem 61-265
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