4-Aminopyridine-d4

Modify Date: 2025-08-27 02:52:57

4-Aminopyridine-d4 Structure
4-Aminopyridine-d4 structure
Common Name 4-Aminopyridine-d4
CAS Number 26257-21-6 Molecular Weight 98.14
Density N/A Boiling Point N/A
Molecular Formula C5H2D4N2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 4-Aminopyridine-d4


4-Aminopyridine-d4 is deuterium labeled 4-Aminopyridine. 4-Aminopyridine is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane.

 Names

Name pyridin-d4-4-amine

 4-Aminopyridine-d4 Biological Activity

Description 4-Aminopyridine-d4 is deuterium labeled 4-Aminopyridine. 4-Aminopyridine is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Sherratt, R.M., H. Bostock, and T.A. Sears, Effects of 4-aminopyridine on normal and demyelinated mammalian nerve fibres. Nature, 1980. 283(5747): p. 570-2.

[3]. Bouchard, R. and D. Fedida, Closed- and open-state binding of 4-aminopyridine to the cloned human potassium channel Kv1.5. J Pharmacol Exp Ther, 1995. 275(2): p. 864-76.

 Chemical & Physical Properties

Molecular Formula C5H2D4N2
Molecular Weight 98.14
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