AG 045572

Modify Date: 2024-02-26 13:24:26

AG 045572 structure	Common Name	AG 045572
	CAS Number	263847-55-8	Molecular Weight	491.62
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀H₃₇NO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AG 045572

AG-045572 is a GnRH receptor antagonist with Kis of 6.0 nM and 3.8 nM for human and rat GnRH receptor, respectively. AG-045572 is metabolized by CYP3A and ressuppresses testosterone[1].

Name	5-[(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)methyl]-N-(2,4,6-trimethoxyphenyl)furan-2-carboxamide
Synonym	More Synonyms

Description	AG-045572 is a GnRH receptor antagonist with Kis of 6.0 nM and 3.8 nM for human and rat GnRH receptor, respectively. AG-045572 is metabolized by CYP3A and ressuppresses testosterone[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> GNRH Receptor Research Areas >> Endocrinology
References	[1]. Iatsimirskaia EA, et al. Effect of testosterone suppression on the pharmacokinetics of a potent gnRH receptor antagonist. Pharm Res. 2002 Feb;19(2):202-8.

Molecular Formula	C₃₀H₃₇NO₅
Molecular Weight	491.62
Exact Mass	491.26700
PSA	69.93000
LogP	6.87890

Ambenonium dichloride

Furan-1

CMPD-1

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-[5,6,7,8-TETRAHYDRO-3,5,5,8,8-PENTAMETHYL-2-NAPHTHALENYL-METHYL]-N-(2,4,6-TRIMETHOXYPHENYL)-2-FURANCARBOXAMIDE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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