DGKα-IN-3

DGKα-IN-3 Structure
DGKα-IN-3 structure
Common Name DGKα-IN-3
CAS Number 2648418-86-2 Molecular Weight 500.51
Density N/A Boiling Point N/A
Molecular Formula C26H27F3N4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DGKα-IN-3


DGKα-IN-3 (example 25) is a DGKα inhibitor with the IC50 of 283 nM, extracted from patent WO2021105115. DGKα-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKα-IN-2 has the potential for cancer and immunology study.

 Names

Name DGKα-IN-3

 DGKα-IN-3 Biological Activity

Description DGKα-IN-3 (example 25) is a DGKα inhibitor with the IC50 of 283 nM, extracted from patent WO2021105115. DGKα-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKα-IN-2 has the potential for cancer and immunology study.
Related Catalog
Target

283 nM (DGKα)

References

[1]. Schmees, Norbert, et al. Preparation of substituted aminoquinolones as DGKα inhibitors for immune activation. WO2021105115.

 Chemical & Physical Properties

Molecular Formula C26H27F3N4O3
Molecular Weight 500.51
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