CIAC001

CIAC001 Structure
CIAC001 structure
Common Name CIAC001
CAS Number 2649154-82-3 Molecular Weight 339.43
Density N/A Boiling Point N/A
Molecular Formula C20H25N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CIAC001


CIAC001 is a Pyruvate Kinase PKM2 inhibitor with anti-neuroinflammatory activity. CIAC001 inhibits LPS-induced proinflammatory nitric oxide (NO) production and protects immunologically active BV-2 cells (IC50=2.5 μM). CIAC001 also has anti-neuroinflammation in mouse models and inhibits chronic morphine-induced addiction[1].

 Names

Name CIAC001

 CIAC001 Biological Activity

Description CIAC001 is a Pyruvate Kinase PKM2 inhibitor with anti-neuroinflammatory activity. CIAC001 inhibits LPS-induced proinflammatory nitric oxide (NO) production and protects immunologically active BV-2 cells (IC50=2.5 μM). CIAC001 also has anti-neuroinflammation in mouse models and inhibits chronic morphine-induced addiction[1].
Related Catalog
Target

PKM2[1]

References

[1]. Jin S, et al. Cannabidiol Analogue CIAC001 for the Treatment of Morphine-Induced Addiction by Targeting PKM2. J Med Chem. 2023 Aug 24;66(16):11498-11516.

 Chemical & Physical Properties

Molecular Formula C20H25N3O2
Molecular Weight 339.43
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