ZDWX-25

Modify Date: 2025-08-21 15:39:53

ZDWX-25 structure	Common Name	ZDWX-25
	CAS Number	2668297-70-7	Molecular Weight	309.32
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₅N₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ZDWX-25

ZDWX-25 is a highly potent GSK-3β and DYRK1A dual inhibitor with an IC50 value of 71 nM for GSK-3β. ZDWX-25 possesses significant cytotoxic activities against SH-SY5Y and HL-7702 cells. ZDWX-25 can be used for researching alzheimer's disease[1].

Name	ZDWX-25

Description	ZDWX-25 is a highly potent GSK-3β and DYRK1A dual inhibitor with an IC50 value of 71 nM for GSK-3β. ZDWX-25 possesses significant cytotoxic activities against SH-SY5Y and HL-7702 cells. ZDWX-25 can be used for researching alzheimer's disease[1].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> GSK-3 Research Areas >> Neurological Disease Signaling Pathways >> PI3K/Akt/mTOR >> GSK-3
Target	GSK-3β:71 nM (IC50)
References	[1]. Liu W, et al. Discovery of novel β-carboline derivatives as selective AChE inhibitors with GSK-3β inhibitory property for the treatment of Alzheimer's disease. Eur J Med Chem. 2022;229:114095.

Molecular Formula	C₁₇H₁₅N₃O₃
Molecular Weight	309.32
InChIKey	HYXRYQYCRBSSIY-UHFFFAOYSA-N
SMILES	COC(=O)c1ccc2c(c1)[nH]c1c(NC(=O)C3CC3)cccc12

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ZDWX-25

Use of ZDWX-25

Names

ZDWX-25 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.