D-erythro-Sphingosine hydrochloride

Modify Date: 2024-01-16 16:14:39

D-erythro-Sphingosine hydrochloride Structure
D-erythro-Sphingosine hydrochloride structure
Common Name D-erythro-Sphingosine hydrochloride
CAS Number 2673-72-5 Molecular Weight 335.95300
Density N/A Boiling Point N/A
Molecular Formula C18H38ClNO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of D-erythro-Sphingosine hydrochloride


D-erythro-Sphingosine (Erythrosphingosine) hydrochloride is a specific TRPM3 activator. D-erythro-Sphingosine also induces retinoblastoma protein dephosphorylation[1][2].

 Names

Name D-erythro-Sphingosine hydrochloride
Synonym More Synonyms

 D-erythro-Sphingosine hydrochloride Biological Activity

Description D-erythro-Sphingosine (Erythrosphingosine) hydrochloride is a specific TRPM3 activator. D-erythro-Sphingosine also induces retinoblastoma protein dephosphorylation[1][2].
Related Catalog
Target

TRPM3

Retinoblastoma protein

In Vitro Extracellular application of D-erythro-Sphingosine (20 μM) induces an increase in [Ca2+]i in TRPM3-transfected HEK293 cells within 20 to 30 s after start of application, whereas nontransfected control cells (NT) shows only very small responses[1]. D-erythro-Sphingosine (10 μM) induces currents through TRPM3[1]. Induction of retinoblastoma protein dephosphorylation by D-erythro-Sphingosine (500 nM; 24 h) precede inhibition of growth and a specific arrest in the G0/G1 phase of the cell cycle[2].

 Chemical & Physical Properties

Molecular Formula C18H38ClNO2
Molecular Weight 335.95300
Exact Mass 335.25900
PSA 66.48000
LogP 5.42650

 Synonyms

d-sphingosine hcl