ETHYL 2,2-DIFLUORO-2-(PYRIDIN-2-YL)ACETATE

Modify Date: 2025-08-23 18:13:41

ETHYL 2,2-DIFLUORO-2-(PYRIDIN-2-YL)ACETATE Structure
ETHYL 2,2-DIFLUORO-2-(PYRIDIN-2-YL)ACETATE structure
Common Name ETHYL 2,2-DIFLUORO-2-(PYRIDIN-2-YL)ACETATE
CAS Number 267876-28-8 Molecular Weight 201.17000
Density 1.228g/cm3 Boiling Point 244.2ºC at 760mmHg
Molecular Formula C9H9F2NO2 Melting Point N/A
MSDS N/A Flash Point 101.5ºC

 Names

Name ethyl 2,2-difluoro-2-pyridin-2-ylacetate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.228g/cm3
Boiling Point 244.2ºC at 760mmHg
Molecular Formula C9H9F2NO2
Molecular Weight 201.17000
Flash Point 101.5ºC
Exact Mass 201.06000
PSA 39.19000
LogP 1.73650
Vapour Pressure 0.031mmHg at 25°C
Index of Refraction 1.46
Storage condition 2-8℃

 Safety Information

Hazard Codes F: Flammable;
HS Code 2933399090

 Synthetic Route

~81%

ETHYL 2,2-DIFLUORO-2-(PYRIDIN-2-YL)ACETATE Structure

ETHYL 2,2-DIFLU...

CAS#:267876-28-8

Literature: Ashwood, Michael S.; Alabaster, Ramon J.; Cottrell, Ian F.; Cowden, Cameron J.; Davies, Antony J.; Dolling, Ulf H.; Emerson, Khateeta M.; Gibb, Andrew D.; Hands, David; Wallace, Debra J.; Wilson, Robert D. Organic Process Research and Development, 2004 , vol. 8, # 2 p. 192 - 200

~%

ETHYL 2,2-DIFLUORO-2-(PYRIDIN-2-YL)ACETATE Structure

ETHYL 2,2-DIFLU...

CAS#:267876-28-8

Literature: Merck and Co., Inc. Patent: US6455532 B1, 2002 ; US 6455532 B1

~77%

ETHYL 2,2-DIFLUORO-2-(PYRIDIN-2-YL)ACETATE Structure

ETHYL 2,2-DIFLU...

CAS#:267876-28-8

Literature: Ashwood, Michael S.; Alabaster, Ramon J.; Cottrell, Ian F.; Cowden, Cameron J.; Davies, Antony J.; Dolling, Ulf H.; Emerson, Khateeta M.; Gibb, Andrew D.; Hands, David; Wallace, Debra J.; Wilson, Robert D. Organic Process Research and Development, 2004 , vol. 8, # 2 p. 192 - 200

~%

ETHYL 2,2-DIFLUORO-2-(PYRIDIN-2-YL)ACETATE Structure

ETHYL 2,2-DIFLU...

CAS#:267876-28-8

Literature: Burgey, Christopher S.; Robinson, Kyle A.; Lyle, Terry A.; Sanderson, Philip E. J.; Lewis, S. Dale; Lucas, Bobby J.; Krueger, Julie A.; Singh, Rominder; Miller-Stein, Cynthia; White, Rebecca B.; Wong, Bradley; Lyle, Elizabeth A.; Williams, Peter D.; Coburn, Craig A.; Dorsey, Bruce D.; Barrow, James C.; Stranieri, Maria T.; Holahan, Marie A.; Sitko, Gary R.; Cook, Jacquelynn J.; McMasters, Daniel R.; McDonough, Colleen M.; Sanders, William M.; Wallace, Audrey A.; Clayton, Franklin C.; Bohn, Dennis; Leonard, Yvonne M.; Detwiler Jr., Theodore J.; Lynch Jr., Joseph J.; Yan, Youwei; Chen, Zhongguo; Kuo, Lawrence; Gardell, Stephen J.; Shafer, Jules A.; Vacca, Joseph P. Journal of Medicinal Chemistry, 2003 , vol. 46, # 4 p. 461 - 473

~%

ETHYL 2,2-DIFLUORO-2-(PYRIDIN-2-YL)ACETATE Structure

ETHYL 2,2-DIFLU...

CAS#:267876-28-8

Literature: Ashwood, Michael S.; Alabaster, Ramon J.; Cottrell, Ian F.; Cowden, Cameron J.; Davies, Antony J.; Dolling, Ulf H.; Emerson, Khateeta M.; Gibb, Andrew D.; Hands, David; Wallace, Debra J.; Wilson, Robert D. Organic Process Research and Development, 2004 , vol. 8, # 2 p. 192 - 200

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

ethyl pyridin-2-yldifluoroacetate
2,2-difluoro-2-pyridin-2-ylacetic acid ethyl ester
ethyl 2,2-difluoro-2-pyridyl acetate
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