CTZ

Modify Date: 2024-01-06 15:44:28

CTZ Structure
CTZ structure
Common Name CTZ
CAS Number 26973-24-0 Molecular Weight 440.481
Density 2.1±0.1 g/cm3 Boiling Point N/A
Molecular Formula C13H12N8O4S3 Melting Point 155ºC (dec.)
MSDS N/A Flash Point N/A

 Use of CTZ


Ceftezole (CTZ) is a broad-spectrum cephem antibiotic against many species of gram-positive and gram-negative bacteria. Ceftezole (CTZ) is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity[1][2].

 Names

Name (6R,7R)-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-3-(1,3,4-thiadiazol-2-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Synonym More Synonyms

 CTZ Biological Activity

Description Ceftezole (CTZ) is a broad-spectrum cephem antibiotic against many species of gram-positive and gram-negative bacteria. Ceftezole (CTZ) is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity[1][2].
Related Catalog
In Vitro Ceftezole is a broad-spectrum antibiotic, active in vitro against many species of gram-positive and gram-negative bacteria except, Serratia marcescens and Proteus vulgaris[1].
References

[1]. Lee DS, et al. Ceftezole, a cephem antibiotic, is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity. Int J Mol Med. 2007 Sep;20(3):379-83.

[2]. Harada Y, et al. Ceftezole, a new cephalosporin C derivative II. Distribution and excretion in parenteral administration. J Antibiot (Tokyo). 1976 Oct;29(10):1071-82.

 Chemical & Physical Properties

Density 2.1±0.1 g/cm3
Melting Point 155ºC (dec.)
Molecular Formula C13H12N8O4S3
Molecular Weight 440.481
Exact Mass 440.014374
PSA 234.93000
LogP 0.87
Index of Refraction 2.003
Storage condition -20℃

 Safety Information

Hazard Codes T+,N
Risk Phrases 21/22-26-50/53
Safety Phrases 28-36/37-45-61
HS Code 3003201400

 Customs

HS Code 3003201400

 Synonyms

Falomesin
Celoslin
(6R)-8-oxo-7t-(2-tetrazol-1-yl-acetylamino)-3-[1,3,4]thiadiazol-2-ylsulfanylmethyl-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
7-(1H-Tetrazol-1-yl)acetamido-3-(1,3,4-thiadiazol-2-ylthio)methylceph-3-em-4-carboxylic Acid
Ceftezol
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 8-oxo-7-[[2-(1H-tetrazol-1-yl)acetyl]amino]-3-[(1,3,4-thiadiazol-2-ylthio)methyl]-, (6R,7R)-
Ceftezole (INN)
CG B3Q
CTZ
MFCD00274176
Demethylcefazolin
(6R,7R)-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-3-[(1,3,4-thiadiazol-2-ylthio)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-3-[(1,3,4-thiadiazol-2-ylthio)methyl]-, (6R,7R)-
(6R,7R)-8-Oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-3-[(1,3,4-thiadiazol-2-ylsulfanyl)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Ceftezole
Ceftezolo
CG-B 3 Q
Ceftezolum