LRRK2-IN-10

Modify Date: 2024-02-05 19:37:28

LRRK2-IN-10 Structure
LRRK2-IN-10 structure
Common Name LRRK2-IN-10
CAS Number 2704562-80-9 Molecular Weight 341.37
Density N/A Boiling Point N/A
Molecular Formula C20H15N5O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LRRK2-IN-10


LRRK2-IN-10 (compound 34) is a potent, mutation-selective, and brain penetrant G2019S-LRRK2 kinase inhibitor with IC50s of 11 nM and 5.2 nM for G2019S-LRRK2 pS935 and G2019S-LRRK2 pS1292, respectively. LRRK2-IN-10 has the potential for Parkinson's disease research[1].

 Names

Name LRRK2-IN-10

 LRRK2-IN-10 Biological Activity

Description LRRK2-IN-10 (compound 34) is a potent, mutation-selective, and brain penetrant G2019S-LRRK2 kinase inhibitor with IC50s of 11 nM and 5.2 nM for G2019S-LRRK2 pS935 and G2019S-LRRK2 pS1292, respectively. LRRK2-IN-10 has the potential for Parkinson's disease research[1].
Related Catalog
References

[1]. Albert W Garofalo, et al. Brain-penetrant cyanoindane and cyanotetralin inhibitors of G2019S-LRRK2 kinase activity.  

 Chemical & Physical Properties

Molecular Formula C20H15N5O
Molecular Weight 341.37
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