DNA-PK-IN-6
Modify Date: 2024-01-05 19:26:30
DNA-PK-IN-6 structure
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Common Name | DNA-PK-IN-6 | ||
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| CAS Number | 2711810-41-0 | Molecular Weight | 363.42 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H21N7O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DNA-PK-IN-6DNA-PK-IN-6 is a potent inhibitor of DNA-PK. DNA-PK-IN-6 inhibits DNA-PKcs activity, thus greatly reducing tumor DNA repair and inducing cells to enter the apoptotic program. DNA-PK-IN-6 enhances the sensitivity of tumor tissues to radiotherapy, overcomes the problem of drug resistance, and enhances the inhibitory effect on a variety of solid tumors and hematological tumors (extracted from patent WO2021197159A1, compound 6)[1]. |
| Name | DNA-PK-IN-6 |
|---|
| Description | DNA-PK-IN-6 is a potent inhibitor of DNA-PK. DNA-PK-IN-6 inhibits DNA-PKcs activity, thus greatly reducing tumor DNA repair and inducing cells to enter the apoptotic program. DNA-PK-IN-6 enhances the sensitivity of tumor tissues to radiotherapy, overcomes the problem of drug resistance, and enhances the inhibitory effect on a variety of solid tumors and hematological tumors (extracted from patent WO2021197159A1, compound 6)[1]. |
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| Related Catalog | |
| References |
[1]. Xinhai Chen, et al. Macrocyclic compounds as dna-pk inhibitors. Patent WO2021197159A1. |
| Molecular Formula | C19H21N7O |
|---|---|
| Molecular Weight | 363.42 |