2711810-41-0

2711810-41-0 structure

Name: DNA-PK-IN-6
Chemical Name: DNA-PK-IN-6
CAS Number: 2711810-41-0
Molecular Formula: C₁₉H₂₁N₇O
Molecular Weight: 363.42
Create Date: 2022-05-20 12:58:54
Modify Date: 2024-01-05 19:26:30
DNA-PK-IN-6 is a potent inhibitor of DNA-PK. DNA-PK-IN-6 inhibits DNA-PKcs activity, thus greatly reducing tumor DNA repair and inducing cells to enter the apoptotic program. DNA-PK-IN-6 enhances the sensitivity of tumor tissues to radiotherapy, overcomes the problem of drug resistance, and enhances the inhibitory effect on a variety of solid tumors and hematological tumors (extracted from patent WO2021197159A1, compound 6)[1].

Name	DNA-PK-IN-6

Description	DNA-PK-IN-6 is a potent inhibitor of DNA-PK. DNA-PK-IN-6 inhibits DNA-PKcs activity, thus greatly reducing tumor DNA repair and inducing cells to enter the apoptotic program. DNA-PK-IN-6 enhances the sensitivity of tumor tissues to radiotherapy, overcomes the problem of drug resistance, and enhances the inhibitory effect on a variety of solid tumors and hematological tumors (extracted from patent WO2021197159A1, compound 6)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> DNA-PK Signaling Pathways >> PI3K/Akt/mTOR >> DNA-PK
References	[1]. Xinhai Chen, et al. Macrocyclic compounds as dna-pk inhibitors. Patent WO2021197159A1.

Molecular Formula	C₁₉H₂₁N₇O
Molecular Weight	363.42