SKLB-197
Modify Date: 2025-08-25 21:35:22
SKLB-197 structure
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Common Name | SKLB-197 | ||
|---|---|---|---|---|
| CAS Number | 2713577-16-1 | Molecular Weight | 424.50 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H24N6O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SKLB-197SKLB-197 showed an IC50 value of 0.013 μM against ATR but very weak or no activity against other 402 protein kinases. It displayed potent antitumor activity against ATM-deficent tumors both in vitro and in vivo. |
| Name | SKLB-197 |
|---|
| Description | SKLB-197 showed an IC50 value of 0.013 μM against ATR but very weak or no activity against other 402 protein kinases. It displayed potent antitumor activity against ATM-deficent tumors both in vitro and in vivo. |
|---|---|
| Related Catalog | |
| Target |
ATR:0.013 μM (IC50) |
| References |
| Molecular Formula | C25H24N6O |
|---|---|
| Molecular Weight | 424.50 |
| InChIKey | FCNFJRRMUAOHKI-MRXNPFEDSA-N |
| SMILES | CC1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2ccc(-c3ccnn3C)cc12 |