ALK/EGFR-IN-1
Modify Date: 2024-01-04 00:56:46
ALK/EGFR-IN-1 structure
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Common Name | ALK/EGFR-IN-1 | ||
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| CAS Number | 2730430-08-5 | Molecular Weight | 572.12 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H34ClN7O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ALK/EGFR-IN-1ALK/EGFR-IN-1 (Compound 8l) is an ALK/EGFR dual inhibitor that blocks the phosphorylation of EGFR and ALK. ALK/EGFR-IN-1 inhibits ALK/EGFR mutants respectively, with IC50 of 4.3 nM for EGFR L858R T790M in H1975 cells and EML4-ALK in BaF3 cells, respectively. and 3.6 nM. ALK/EGFR-IN-1 may be used in NSCLC research[1]. |
| Name | ALK/EGFR-IN-1 |
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| Description | ALK/EGFR-IN-1 (Compound 8l) is an ALK/EGFR dual inhibitor that blocks the phosphorylation of EGFR and ALK. ALK/EGFR-IN-1 inhibits ALK/EGFR mutants respectively, with IC50 of 4.3 nM for EGFR L858R T790M in H1975 cells and EML4-ALK in BaF3 cells, respectively. and 3.6 nM. ALK/EGFR-IN-1 may be used in NSCLC research[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C27H34ClN7O3S |
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| Molecular Weight | 572.12 |