Norflurazon
Norflurazon structure
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Common Name | Norflurazon | ||
|---|---|---|---|---|
| CAS Number | 27314-13-2 | Molecular Weight | 303.67 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 345.2±52.0 °C at 760 mmHg | |
| Molecular Formula | C12H9ClF3N3O | Melting Point | 184ºC | |
| MSDS | Chinese USA | Flash Point | 162.6±30.7 °C | |
| Symbol |
GHS09 |
Signal Word | Warning | |
Use of NorflurazonNorflurazon (SAN 9789) is a bleaching herbicide. Norflurazon can block carotenoid biosynthesis by inhibiting phytoene desaturase activity[1]. |
Summary: Norflurazon, with Chinese name as norflurazon, has CAS number 27314-13-2, molecular formula C12H9ClF3N3O, and molecular weight 303.67. It is a crystalline white solid with a melting point of 184°C and a boiling point of 345.2±52.0 °C, and a density of 1.5±0.1 g/cm3. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | norflurazon |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Norflurazon (SAN 9789) is a bleaching herbicide. Norflurazon can block carotenoid biosynthesis by inhibiting phytoene desaturase activity[1]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 345.2±52.0 °C at 760 mmHg |
| Melting Point | 184ºC |
| Molecular Formula | C12H9ClF3N3O |
| Molecular Weight | 303.67 |
| Flash Point | 162.6±30.7 °C |
| Exact Mass | 303.038635 |
| PSA | 46.92000 |
| LogP | 2.45 |
| Appearance of Characters | Crystalline Solid | White |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.567 |
| InChIKey | NVGOPFQZYCNLDU-UHFFFAOYSA-N |
| SMILES | CNc1cnn(-c2cccc(C(F)(F)F)c2)c(=O)c1Cl |
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H400 |
| Precautionary Statements | P273 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | N: Dangerous for the environment; |
| Risk Phrases | R50 |
| Safety Phrases | 61 |
| RIDADR | UN 3077 9/PG 3 |
| RTECS | UR6150000 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~18%
Norflurazon CAS#:27314-13-2 |
| Literature: Konecny, Vaclav; Kovac, Stefan; Varkonda, Stefan Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 2 p. 492 - 502 |
![4,5-dichloro-2-[3-(trifluoromethyl)phenyl]pyridazin-3(2H)-one structure](https://image.chemsrc.com/caspic/360/26806-47-3.png)
This table lists relevant public references with title, journal and publication metadata for this compound.
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A new F131V mutation in Chlamydomonas phytoene desaturase locates a cluster of norflurazon resistance mutations near the FAD-binding site in 3D protein models.
PLoS ONE 9(6) , e99894, (2014) The green alga Chlamydomonas reinhardtii provides a tractable genetic model to study herbicide mode of action using forward genetics. The herbicide norflurazon inhibits phytoene desaturase, which is r... |
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Novel bioassay for the discovery of inhibitors of the 2-C-methyl-D-erythritol 4-phosphate (MEP) and terpenoid pathways leading to carotenoid biosynthesis.
PLoS ONE 9(7) , e103704, (2014) The 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway leads to the synthesis of isopentenyl diphosphate in plastids. It is a major branch point providing precursors for the synthesis of carotenoids, t... |
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Functional characterization of the two ferrochelatases in Arabidopsis thaliana.
Plant Cell Environ. 38(2) , 280-98, (2015) The enzyme ferrochelatase catalyses the formation of protoheme by inserting Fe(2+) into protoporphyrin IX. Although most organisms express only one ferrochelatase, all land plants analysed so far poss... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 4-Chlor-5-(methylamino)-2-[3-(trifluormethyl)phenyl]pyridazin-3(2H)-on |
| 4-Chloro-5-(methylamino)-2-[3-(trifluoromethyl)phenyl]pyridazin-3(2H)-one |
| 4-Chloro-5-(methylamino)-2-(a,a,a-trifluoro-m-tolyl)-3(2H)-pyridazinone |
| 4-Chloro-5-(methylamino)-2-(α,α,α-trifluoro-m-tolyl)-3(2H)-pyridazinone |
| EINECS 248-397-1 |
| MFCD00128055 |
| 4-chloro-5-methylamino-2-(α,α,α-trifluoro-m-tolyl)pyridazin-3(2H)-one |
| 4-Chloro-5-(methylamino)-2-[3-(trifluoromethyl)phenyl]-3(2H)-pyridazinone |
| 4-Chloro-5-(methylamino)-2-(3-(trifluoromethyl)phenyl)-3(2H)-pyridazinone (9CI) |
| 4-chloro-5-(methylamino)-2-[3-(trifluoromethyl)phenyl]pyridazin-3-one |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the uses of norflurazon? |
| A: Main uses of norflurazon: Norflurazon (SAN 9789) is a bleaching herbicide. Norflurazon can block carotenoid biosynthesis by inhibiting phytoene desaturase activity[1]. |
| Q: What is the LogP of norflurazon? |
| A: LogP of norflurazon is 2.45. |
| Q: What is the SMILES notation of norflurazon? |
| A: SMILES notation of norflurazon is CNc1cnn(-c2cccc(C(F)(F)F)c2)c(=O)c1Cl. |
| Q: What is the molecular weight of norflurazon? |
| A: Molecular weight of norflurazon is 303.67. |
| Q: What is the polar surface area (PSA) of norflurazon? |
| A: Polar surface area (PSA) of norflurazon is 46.92000. |
| Q: What is the safety information for norflurazon? |
| A: Safety information for norflurazon: 61. |
| Q: What is the CAS number of norflurazon? |
| A: CAS number of norflurazon is 27314-13-2. |
| Q: What is the English name of norflurazon? |
| A: The English name of norflurazon is norflurazon. |
| Q: What is the physical appearance of norflurazon? |
| A: norflurazon appears as Crystalline Solid | White. |
| Q: What is the melting point of norflurazon? |
| A: Melting point of norflurazon is 184ºC. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |