Indolizine
Modify Date: 2026-07-06 22:15:04
Indolizine structure
|
Common Name | Indolizine | ||
|---|---|---|---|---|
| CAS Number | 274-40-8 | Molecular Weight | 117.148 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 202 °C at 760 mmHg (lit.) | |
| Molecular Formula | C8H7N | Melting Point | 72°C (lit.) | |
| MSDS | N/A | Flash Point | N/A | |
Summary: Indolizine, Chinese name: 吲哚嗪 (CAS number: 274-40-8), has a molecular formula of C8H7N and a molecular weight of 117.148. It is a solid or liquid with a melting point of 72°C and a boiling point of 202°C. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | indolizine |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 202 °C at 760 mmHg (lit.) |
| Melting Point | 72°C (lit.) |
| Molecular Formula | C8H7N |
| Molecular Weight | 117.148 |
| Exact Mass | 117.057846 |
| PSA | 4.41000 |
| LogP | 2.49 |
| Index of Refraction | 1.581 |
| InChIKey | HOBCFUWDNJPFHB-UHFFFAOYSA-N |
| SMILES | c1ccn2cccc2c1 |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
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Pyrrolo[1,2-a]pyridine
Revision number: 5
SAFETY DATA SHEET Section1. IDENTIFICATION Product name:Pyrrolo[1,2-a]pyridine Revision number:5 Section2. HAZARDS IDENTIFICATION GHS classification PHYSICAL HAZARDSNot classified HEALTH HAZARDS Skin corrosion/irritationCategory 2 Category 2A Serious eye damage/eye irritation ENVIRONMENTAL HAZARDSNot classified GHS label elements, including precautionary statements Pictograms or hazard symbols Signal wordWarning Hazard statementsCauses skin irritation Causes serious eye irritation Precautionary statements: Wash hands thoroughly after handling. [Prevention] Wear protective gloves/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, [Response] if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention. IF ON SKIN: Gently wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Section3. COMPOSITION/INFORMATION ON INGREDIENTS Substance/mixture:Substance Components:Pyrrolo[1,2-a]pyridine Percent:>98.0%(GC)(T) CAS Number:274-40-8 Synonyms:4-Azaindene , Indolizine C8H7N Chemical Formula: Section4. FIRST AID MEASURES Inhalation:Remove victim to fresh air and keep at rest in a position comfortable for breathing. Get medical advice/attention if you feel unwell. Pyrrolo[1,2-a]pyridine Section4. FIRST AID MEASURES Skin contact:Remove/Take off immediately all contaminated clothing. Gently wash with plenty of soap and water. If skin irritation or rash occurs: Get medical advice/attention. Eye contact:Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention. Ingestion:Get medical advice/attention if you feel unwell. Rinse mouth. A rescuer should wear personal protective equipment, such as rubber gloves and air- Protection of first-aiders: tight goggles. Section5. FIRE-FIGHTING MEASURES Suitable extinguishingDry chemical, foam, water spray, carbon dioxide. media: Specific hazards arising Take care as it may decompose upon combustion or in high temperatures to from the chemical:generate poisonous fume. Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place. In case of fire in the surroundings: Remove movable containers if safe to do so. Special protectiveWhen extinguishing fire, be sure to wear personal protective equipment. equipment for firefighters: Section6. ACCIDENTAL RELEASE MEASURES Personal precautions,Use personal protective equipment. Keep people away from and upwind of spill/leak. protective equipment and Entry to non-involved personnel should be controlled around the leakage area by emergency procedures: roping off, etc. Environmental precautions: Prevent product from entering drains. Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it. containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with up: appropriate laws and regulations. Section7. HANDLING AND STORAGE Precautions for safe handling Technical measures:Handling is performed in a well ventilated place. Wear suitable protective equipment. Prevent dispersion of dust. Wash hands and face thoroughly after handling. Use a local exhaust if dust or aerosol will be generated. Advice on safe handling: Avoid contact with skin, eyes and clothing. Conditions for safe storage, including any incompatibilities Storage conditions:Keep container tightly closed. Store in a freezer. Store under inert gas. Store away from incompatible materials such as oxidizing agents. Heat-sensitive, Air-sensitive Packaging material:Comply with laws. Section8. EXPOSURE CONTROLS / PERSONAL PROTECTION Engineering controls:Install a closed system or local exhaust as possible so that workers should not be exposed directly. Also install safety shower and eye bath. Personal protective equipment Respiratory protection: Dust respirator. Follow local and national regulations. Hand protection:Protective gloves. Safety glasses. A face-shield, if the situation requires. Eye protection: Skin and body protection: Protective clothing. Protective boots, if the situation requires. Section9. PHYSICAL AND CHEMICAL PROPERTIES Physical state (20°C):Solid Crystal- Powder Form: Pyrrolo[1,2-a]pyridine Section9. PHYSICAL AND CHEMICAL PROPERTIES Colour:White - Very pale yellow Odour:No data available pH: No data available Melting point/freezing point:74°C Boiling point/range:202°C Flash point:No data available Flammability or explosive limits: Lower:No data available Upper:No data available Relative density:No data available Solubility(ies): [Water]No data available [Other solvents]No data available Section10. STABILITY AND REACTIVITY Stable under proper conditions. Chemical stability: Possibility of hazardous No special reactivity has been reported. reactions: Incompatible materials: Oxidizing agents Hazardous decomposition Carbon monoxide, Carbon dioxide, Nitrogen oxides (NOx) products: Section11. TOXICOLOGICAL INFORMATION Acute Toxicity:No data available Skin corrosion/irritation: No data available Serious eyeNo data available damage/irritation: Germ cell mutagenicity: No data available Carcinogenicity: IARC =No data available NTP =No data available Reproductive toxicity:No data available Section12. ECOLOGICAL INFORMATION Ecotoxicity: Fish:No data available No data available Crustacea: Algae:No data available Persistence / degradability: No data available BioaccumulativeNo data available potential(BCF): Mobility in soil Log Pow:No data available Soil adsorption (Koc):No data available No data available Henry's Law constant(PaM3/mol): Section13. DISPOSAL CONSIDERATIONS Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all federal, state and local regulations when disposing of the substance. Section14. TRANSPORT INFORMATION Hazards Class:Does not correspond to the classification standard of the United Nations UN-No:Not listed Pyrrolo[1,2-a]pyridine Section15. REGULATORY INFORMATION Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002 and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport, loading and unloading were prescribed. SECTION 16 - ADDITIONAL INFORMATION N/A |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Hazard Codes | Xi |
|---|---|
| HS Code | 2933990090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 8 | |
|---|---|
| DownStream 0 | |
CAS#:2859-68-9
CAS#:35469-62-6
CAS#:123471-47-6
CAS#:17282-40-5
CAS#:100391-74-0
CAS#:3189-48-8
CAS#:525-42-8
CAS#:251-60-5This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| pyrrolo[b]pyridine |
| Pyrrolo[1,2-a]pyridine |
| Indolizin |
| Pyrrocoline |
| Indolizine |
| Pyrrolo(1,2-a)pyridine |
| 4-Azaindene |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the English name of indolizine? |
| A: The English name of indolizine is indolizine. |
| Q: What is the polar surface area (PSA) of indolizine? |
| A: Polar surface area (PSA) of indolizine is 4.41000. |
| Q: What is the molecular weight of indolizine? |
| A: Molecular weight of indolizine is 117.148. |
| Q: What is the CAS number of indolizine? |
| A: CAS number of indolizine is 274-40-8. |
| Q: What is the InChIKey of indolizine? |
| A: InChIKey of indolizine is HOBCFUWDNJPFHB-UHFFFAOYSA-N. |
| Q: What are the upstream materials of indolizine? |
| A: Related upstream materials(CAS) of indolizine: 2859-68-9;35469-62-6;123471-47-6;17282-40-5;100391-74-0;3189-48-8;525-42-8;251-60-5. |
| Q: What is the molecular formula of indolizine? |
| A: Molecular formula of indolizine is C8H7N. |
| Q: What is the melting point of indolizine? |
| A: Melting point of indolizine is 72°C (lit.). |
| Q: What is the SMILES notation of indolizine? |
| A: SMILES notation of indolizine is c1ccn2cccc2c1. |
| Q: What English synonyms does indolizine have? |
| A: English synonyms of indolizine: pyrrolo[b]pyridine, Pyrrolo[1,2-a]pyridine, Indolizin, Pyrrocoline, Indolizine, Pyrrolo(1,2-a)pyridine, 4-Azaindene. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |