(16β,22R)-14α,17-Epoxy-13,14,20,22-tetrahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone

Modify Date: 2024-01-14 07:42:14

(16β,22R)-14α,17-Epoxy-13,14,20,22-tetrahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone Structure
(16β,22R)-14α,17-Epoxy-13,14,20,22-tetrahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone structure
Common Name (16β,22R)-14α,17-Epoxy-13,14,20,22-tetrahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone
CAS Number 27503-33-9 Molecular Weight 510.53200
Density N/A Boiling Point N/A
Molecular Formula C28H30O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (16β,22R)-14α,17-Epoxy-13,14,20,22-tetrahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone


Physalin C is a natural product that can be found in physalis angulata. Physalin C shows cytotoxic activities against MCF-7 and HepG2 cells[1].

 Names

Name Physalin C

  Biological Activity

Description Physalin C is a natural product that can be found in physalis angulata. Physalin C shows cytotoxic activities against MCF-7 and HepG2 cells[1].
Related Catalog
In Vitro Physalin C (compound 6) (0-100 µM; 72 h) 显示出对 MCF-7 和 HepG2 细胞的细胞毒活性,IC50 分别为 10.5、24.2 µM[1]。 Cell Cytotoxicity Assay[1] Cell Line: MCF-7,HepG2 cells Concentration: 0-100 µM Incubation Time: 72 h Result: Showed cytotoxic activities with IC50s of 10.5, 24.2 µM for MCF-7,HepG2 cells, respectively.
References

[1]. Jia-Jia Fan, et al. A Novel Cytotoxic Physalin from Physalis angulata. Natural Product Communications, 2017, 12(10):1589-1591.

 Chemical & Physical Properties

Molecular Formula C28H30O9
Molecular Weight 510.53200
Exact Mass 510.18900
PSA 136.43000
LogP 1.45910

 Safety Information

Hazard Codes Xi