SOS1-IN-8
Modify Date: 2025-08-27 19:57:31
SOS1-IN-8 structure
|
Common Name | SOS1-IN-8 | ||
|---|---|---|---|---|
| CAS Number | 2759387-92-1 | Molecular Weight | 477.48 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H26F3N3O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SOS1-IN-8SOS1-IN-8 is a potent SOS1 inhibitor with IC50s of 11.6 and 40.7 nM for SOS1-G12D and SOS1-G12V, respectively (WO2022017339A1, compound 2)[1]. |
| Name | SOS1-IN-8 |
|---|
| Description | SOS1-IN-8 is a potent SOS1 inhibitor with IC50s of 11.6 and 40.7 nM for SOS1-G12D and SOS1-G12V, respectively (WO2022017339A1, compound 2)[1]. |
|---|---|
| Related Catalog | |
| Target |
SOS1-G12D:11.6 nM (IC50) SOS1-G12V:40.7 nM (IC50) |
| References |
| Molecular Formula | C24H26F3N3O4 |
|---|---|
| Molecular Weight | 477.48 |
| InChIKey | AXFAPMWBBDBMMZ-HIFRSBDPSA-N |
| SMILES | COc1cc2c(C)nnc(NC(C)c3cccc(C(F)(F)CO)c3F)c2cc1OC1CCOC1 |