LMTK3-IN-1
Modify Date: 2024-01-08 11:18:41
LMTK3-IN-1 structure
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Common Name | LMTK3-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 2764850-23-7 | Molecular Weight | 356.30 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H11F3N4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of LMTK3-IN-1LMTK3-IN-1 (compound C28) is an ATP-competitive inhibitor of lemur tyrosine kinase 3 (LMTK3) (Kd=2.5 μM)，that acts by degrading LMTK3 via the ubiquitin-proteasome pathway. LMTK3-IN-1 shows anticancer activity in a variety of cancer cell lines and in vivo BC mouse models. LMTK3-IN-1 induces apoptosis in BC cell lines at 10-20 μM[1]. |
| Name | LMTK3-IN-1 |
|---|
| Description | LMTK3-IN-1 (compound C28) is an ATP-competitive inhibitor of lemur tyrosine kinase 3 (LMTK3) (Kd=2.5 μM)，that acts by degrading LMTK3 via the ubiquitin-proteasome pathway. LMTK3-IN-1 shows anticancer activity in a variety of cancer cell lines and in vivo BC mouse models. LMTK3-IN-1 induces apoptosis in BC cell lines at 10-20 μM[1]. |
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| Related Catalog | |
| Target |
LMTK3[1] |
| References |
| Molecular Formula | C18H11F3N4O |
|---|---|
| Molecular Weight | 356.30 |