PD-1/PD-L1-IN-32

Modify Date: 2024-01-04 20:09:50

PD-1/PD-L1-IN-32 structure	Common Name	PD-1/PD-L1-IN-32
	CAS Number	2765535-21-3	Molecular Weight	517.98
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₂₅ClFN₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PD-1/PD-L1-IN-32

PD-1/PD-L1-IN-32 (compound A56) is a potent PD-1/PD-L1 inhibitor (IC50=2.4 nM), with anticancer activity. PD-1/PD-L1-IN-32 significantly inhibits tumor growth in hPD-L1 MC38 humanized mouse model, without obvious toxicity against mouse normal ability[1].

Name	PD-1/PD-L1-IN-32

Description	PD-1/PD-L1-IN-32 (compound A56) is a potent PD-1/PD-L1 inhibitor (IC50=2.4 nM), with anticancer activity. PD-1/PD-L1-IN-32 significantly inhibits tumor growth in hPD-L1 MC38 humanized mouse model, without obvious toxicity against mouse normal ability[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> PD-1/PD-L1
Target	IC50: 2.4 nM (PD-1/PD-L1)[1]
References	[1]. Zhang H, et al. Design, Synthesis, and Antitumor Activity Evaluation of 2-Arylmethoxy-4-(2,2'-dihalogen-substituted biphenyl-3-ylmethoxy) Benzylamine Derivatives as Potent PD-1/PD-L1 Inhibitors. J Med Chem. 2023 Aug 10;66(15):10579-10603.

Molecular Formula	C₂₉H₂₅ClFN₃O₃
Molecular Weight	517.98

PD-1/PD-L1-IN-32

Use of PD-1/PD-L1-IN-32

Names

PD-1/PD-L1-IN-32 Biological Activity

Chemical & Physical Properties