ALPK1-IN-2

Modify Date: 2025-08-26 17:27:03

ALPK1-IN-2 structure	Common Name	ALPK1-IN-2
	CAS Number	2765633-68-7	Molecular Weight	416.44
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₈F₂N₄O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ALPK1-IN-2

ALPK1-IN-2 (compound T001) is a potent ALPK1 (alpha-kinase 1) inhibitor, with an IC50 of 95 nM. ALPK1-IN-2 also inhibits NF-κB, with an IC50 of 1.31 μM[1].

Name	ALPK1-IN-2

Description	ALPK1-IN-2 (compound T001) is a potent ALPK1 (alpha-kinase 1) inhibitor, with an IC50 of 95 nM. ALPK1-IN-2 also inhibits NF-κB, with an IC50 of 1.31 μM[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology
Target	IC50: 95 nM (ALPK1), 1.31 μM (NF-κB)[1]
References	[1]. Danyang Liu, et al. Benzothiazole and quinoline derivatives and their use. WO2022063153A1.

Molecular Formula	C₂₀H₁₈F₂N₄O₂S
Molecular Weight	416.44
InChIKey	SHSJEVPKHXWBHO-UHFFFAOYSA-N
SMILES	COc1cccc2sc(NC(=O)c3c(F)cc(N4CC5CC(C4)N5)cc3F)nc12

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