MK-1468

Modify Date: 2024-01-02 18:33:00

MK-1468 Structure
MK-1468 structure
Common Name MK-1468
CAS Number 2769107-89-1 Molecular Weight 501.02
Density N/A Boiling Point N/A
Molecular Formula C26H33ClN4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MK-1468


MK-1468 is a high selective and brain-penetrant inhibitor of LRRK2 with an IC50 of 0.8 nM. MK-1468 can be used in study Parkinson’s disease[1].

 Names

Name MK-1468

 MK-1468 Biological Activity

Description MK-1468 is a high selective and brain-penetrant inhibitor of LRRK2 with an IC50 of 0.8 nM. MK-1468 can be used in study Parkinson’s disease[1].
Related Catalog
References

[1]. Kattar SD, et al. Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson's Disease. J Med Chem. 2023 Oct 20.  

 Chemical & Physical Properties

Molecular Formula C26H33ClN4O4
Molecular Weight 501.02