Tolindate

Modify Date: 2024-01-25 05:58:42

Tolindate Structure
Tolindate structure
Common Name Tolindate
CAS Number 27877-51-6 Molecular Weight 297.41500
Density 1.208g/cm3 Boiling Point 425.1ºC at 760mmHg
Molecular Formula C18H19NOS Melting Point N/A
MSDS N/A Flash Point 210.9ºC

 Use of Tolindate


Tolindate is a potent PXR agonist with an EC50 value of 8.3 µM. Tolindate shows antifungal activity[1][2].

 Names

Name O-(2,3-dihydro-1H-inden-5-yl) N-methyl-N-(3-methylphenyl)carbamothioate
Synonym More Synonyms

 Tolindate Biological Activity

Description Tolindate is a potent PXR agonist with an EC50 value of 8.3 µM. Tolindate shows antifungal activity[1][2].
Related Catalog
In Vitro Tolindate (0-100 µM; 24 h) with the presence of SPA70 (0.5, 7.5 µM) shows significantly induces CYP3A4 in hPXR HepG2 cells[1].

 Chemical & Physical Properties

Density 1.208g/cm3
Boiling Point 425.1ºC at 760mmHg
Molecular Formula C18H19NOS
Molecular Weight 297.41500
Flash Point 210.9ºC
Exact Mass 297.11900
PSA 44.56000
LogP 4.28380
Vapour Pressure 1.96E-07mmHg at 25°C
Index of Refraction 1.662

 Safety Information

HS Code 2930909090

 Customs

HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

Tolindat
Tolindate (USAN/INN)
Tolindatum
Tolindata
TOLINDATE
Tolindato